Module 38Dengue and West Nile VirusesDescribe the virions and genomes - Single Stranded (+) RNA genome - About 11 kb- Enveloped virus - Genome directly translated - Cytoplasmic replication - Double stranded RNA intermediate- viral RNA - polymerase necessary - Flaviviruses: Dengue, West Nile, Yellow Fever, and Zika VirusIdentify the vector - Mosquito- virus could come from another human for dengue or monkeycome from bird or another human for west nileDiscuss the disease presentation- can cause hemorrhagic fever-dengue more symptomatic - can cause meningitis-west nileExplain where are the diseases are foundDengue fever found in Asia and Latin AmericaOutline the control methods- kill mosquito- pesticides- Irrdicate male mosquitoZika VirusOutline the rapid pace of the epidemic- meningitis spreads quickly- infection of brain- can be deadly within 8 hoursIdentify genome and virion characteristicsSingle stranded rna +, enveloped, flavivirusList the disease symptoms and fatality rateLess than 1%, fever, but leads to birth defectsDefine microcephalySmall cranium in newbornsDescribe Guillain-BarrésyndroNeurological disorder, causes difficulty with walking, muscular disorder, due to an immune
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