MMG301 1nd Edition Lecture 30Outline of Last Lecture I. Plant microbe interactionsOutline of Current Lecture II. Human microbe interactionsCurrent Lecture-disease: damage or injury to the host in which host function is impaired-pathogen: any disease-producing organism -pathogenicity: the ability to produce harmful pathologic changes or disease-virulence: quantitative measure of pathogenicity-infection: growth of microbes inside the host tissues; the host may or may not be harmed-normal microflora: mixture of microbes normally found at any anatomical site in a healthy organism-human micribiome: the sum total of all the microbial cells in and on us-Gnotobiotic : ”known flora”-Gnotobiotic animals-Allow investigation of interactions with specific microorganisms deliberately introduced into the animal-Mammals: mice, pigs, -Chickens -Colonies of germ-free animals are maintained and monitored in sterile environments-Colonization of the gingival and tooth surface involves formation of a biofilm-Begins as layer of glycoprotein on surface of clean toothThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.-Attachment and colonization by several Streptococcus-Continued growth results in thick layer called plaque-Dental caries: colonization of tooth crevices by microorganisms followed by demineralization oftooth surface (sugar fermentation to lactic acid)-Streptococcus sobrinus – has affinity for salivary glycoproteins; has significant role intooth decay; aids in biofilm formation-Streptococcus mutans – aids biofilm formation-Adheres to tooth surface with aid of dextran (a polysaccharide)-Gingivitis: infection of the gingival crevice resulting in tissue inflammation and underlying bone
View Full Document
Unlocking...