[MMG301 Merrill] L29IndMicPt2.docPage 1Industrial Microbiology: Pt 2[Perry, et al., 2002 Microbial Life, Ch. 31]I. EnzymesA. See Table 31.7B. Examples:1. Production of high fructose corn syrup2. Taq PolymeraseII. Microbial TransformationsA. specific example: steroids1. substitutions on basic steroid nucleus: (See Fig. 31.14)[MMG301 Merrill] L29IndMicPt2.docPage 2III. Inhibitors:A. biocides1. Bacillus thuringiensis: “Bt-toxin”2. See Fig. 31.16:[MMG301 Merrill] L29IndMicPt2.docPage 3B. Antibiotics(1) penicillin(2) beta-lactam ring: see Fig. 31.21b) Cephalosporin(1) see Fig. 31.22c) Streptomycin(1) see Fig. 31.23[MMG301 Merrill] L29IndMicPt2.docPage 4d) Macrocyclic Lactones = macrolides(1) see fig. 31.24e) Tetracylines(1) see Fig. 31.25IV. Genetically Engineered MicrobesA. Examples:1. Human Insulin(1) See Fig. 31.262. Human Growth Hormonea)
View Full Document
Unlocking...