MMG301 1nd Edition Lecture 11 Outline of Last Lecture I. EukaryotesOutline of Current Lecture II. Major components of a bacterial cellIII. Gram positive bacteriaIV. Gram negative bacteriaV. Function of the LPSCurrent Lecture-major components of a bacterial cell-cell envelope: keeps cell intact, is a selective transport barrier-surface appendages: various functions-internal matrix: cytoplasm, nucleic acids and other elements-gram positive bacteria-very thick cross linked peptidoglycan-no outer membrane-gram negative bacteria-thin peptidoglycan within a periplasmic space-outer membrane-gram negative cell envelope-cytoplasmic membrane-phospholipid bilayer and various proteins-outer membraneThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.-inner leaflet: phospholipids and proteins-outer leaflet: lipopolysaccharide (LPS), phospholipids and proteins-periplasm-functions of the LPS-major structural component of the OM -lipid A: essential for the formation, stabilization, and function of the OM, thus viability and growth of the cell-toxicity to animals: (LPS = endotoxin). Responsible for a number of bacterial illnesses like salmonella -localization of specific proteins to the OM; these proteins function in close association with LPS -protection against entry of certain toxic extracellular substances into the cell -specificity of recognition: O-specific polysaccharide recognized by bacteriophages and by immune system of warm-blooded animals; can protect from
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