Progress Report 1 Date 2 September to 8 September 2005 Project Bioactive Interference Screw Client William Murphy Ph D Members Katherine Davis BSAC Aaron Huser BWIG Cole Kreofsky BSAC Dana Nadler Communicator Joe Poblocki Team Leader Problem Statement Currently during an ACL reconstructive surgery titanium or partially degradable interference screws are used to secure the graft within the femur and tibia These screws or parts of these screws will remain in the patient s knee for the rest of his or her life and can cause problems The current screws are also not conducive for tissue re growth It is therefore our client s desire to develop a biphasic interference screw for ACL reconstruction that will promote and foster the growth of surrounding bone tissue as well as limit any potential problems a patient may incur due to these screws in his or her body Summary of Accomplishments We have recapped what our immediate and long term goals are for this project We also introduced the problem to our new member Kate Roles were further assigned for the semester along with duties hoped to be accomplished in the next couple weeks Hours Group Met to discuss aspects of project that needed to be accomplished 0 5 hours Contacted and met with client Prof Murphy 0 5 hours Contacted and gained information RE Rapid Prototyping 0 5 hours Went to hardware store to search for Alternative temporary mold TOTAL Goals for 9 8 05 9 15 05 Find temporary mold to use until rapid prototyping is finished Look into casting possibilities once mold is created Discuss with ME shop what needs to be done to get mold Order appropriate plastic to mimic PLGA properties for early testing 1 0 hour 2 5 hours Problems making a reproducible mold before RP process September Task Website Update 16 23 30 7 14 November 21 28 4 11 18 December 25 2 Final Poster Presentation Mold Development Computer Model Bullet Mold Screw Synthesis Rapid Prototyping Metal Casting Modifications and Refinement Materials of Screw Alginate Mineralization Polymer Ratio Testing Materials Prototype In Vitro Degradation Mineralized Alginate Properties Screw Mechanical Properties Interface Dynamics Team Building Meetings Client Formal or Informal Advisor Deliverables Progress Reports Midterm Presentation Final Poster Presentation Final Report 9 Midsemester Presentation Continued Background Research 2 October 9
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