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Lecture 8 Mendel s Second Law vs Chromosome Theory Mendel AaBb can pass on AB Ab aB ab Chromosome contradicts Mendel s second law because of the A and B alleles are on the same chromosome all four gametes cannot be formed Fruit Fly Genetics and Linkage Obtained mutant Drosophila and crossed them Wild type means normal Proportion of recombinants of non parental type total Alfred Sturtevant created a linkage map to explain the proportion of recombinants we were seeing He puts together many two factor crosses and uses them to create the rst genetic map Linkage Three factor crosses Chromosomal Base of Sex Male X and Y chromosomes Female X and X chromosomes Bird males Z and Z chromosomes Bird females Z and W chromosomes Worm males X and X chromosomes Worm females X chromosome


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MIT 7 012 - Lecture 8

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