BIO 446L 1st Edition Lecture 37 Outline of Last Lecture I. Male reproductive system contda. Spermatogenesisb. Spermiogenesisc. Intratesticular and genital ductd. Epididymisi. Decapitation factore. Ductus deferensf. Accessory glands- seminal vesiclesi. Principle cellsg. Prostate glandi. Prostate cancerOutline of Current Lecture I. Male reproductive system contd.a. Penisi. Corpus cavernosaii. Corpus spongiosumiii. Parasympatheticiv. SympatheticThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.b. Viagra storyi. Role of nitric oxideii. Pulmonary hypertensionCurrent Lecture- Male Reproductive System contd.o Penis Structures enclosed by tunica albugenia Corpus cavernosa- Central artery passes through these columns of erectile tissue Corpus spongiosum- Urethra passes through Parasympathetic response—dilation of central and helicine arteries- Causes corpus to swell and outflow veins close, erection occurs Sympathetic response—constricts inflow arteries and opens veins for flowout of erectile tissue- Allows erection to be lost and ejaculation occurs o Viagra Story Ach dilates blood vessels Role of nitric oxide- Parasympathetic innervation to smooth muscle in peniso Release Ach and NO NO is a cofactor that diffuses into smooth muscle and promotes GMP conversion to cyclic GMP Cyclic GMP relaxes smooth muscles- Allows erection Phosphodiesterase breaks down cyclic GMP- Erection is lost Viagra is a phosphodiesterase inhibitor- Prevents breakdown of cGMP to maintain an erection Pulmonary (right sided) hypertension- The smooth muscle relaxation properties of Viagra allows it, along with other phosphodiesterase inhibitors, to be used for pulmonary
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