BIO 446L 1st Edition Lecture 33 Outline of Last Lecture I. The Integumentary Systema. Anatomyb. The epidermisi. Stratum layersc. Melanocytesd. The dermisi. Reticular and papillary layerii. Blood supplyiii. Sensory receptorsiv. Hairv. Skin wound repairvi. Sebaceous and sweat glands1. Light cells and dark cellsOutline of Current Lecture I. Female Reproductive Systema. Anatomyb. Follicles of the ovaryi. Primordial and primary folliclesThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.1. Layersii. Secondary follicles and atresiac. Oogenesisd. Ovulation e. Corpus luteumf. Uterine tubeCurrent Lecture- Female Reproductive Anatomyo Functions Procreation Production of gametes Ovaries are the gonads Uterine tube not attached to ovaryo Cortex= developing follicleso Two blood supplies Ovary—ovarian artery Uteres—uteran artery- Follicles of the ovaryo Gonads develop early in gestation Ovaries and testes migrate to the same placeo Primordial follicles Number decreases from gestation to birth—few hundred thousando Phenotype change does occur Folds At any time in cycling female you will see all stageso Birth Primary osscytes arrested in prophase 1o Puberty FSH 1 layer of epithelial cells- Primordialo Corpus luteum 2nd follicle Moves from first oocyte to second oocyte- Finishes meiosis 1 and goes to meiosis 2o Corpus albacano Primary oocytes and primary follicle 2P: layer that surrounds oocyteso Second follicle Fluid filled space with primary oocyteo Ovulates oocyte Very large fluid filled granulosa, thinned out everywhere beside oocyte- Primordial and Primary Follicleso FSH stimulates developmento ZP protein Receptors for sperm Produce enzymes that activate sperm cellso Tunica albagenia One layer of epithelial cellso Granulosa/oocytes put out projections that can move through network via gap junctionso Mecacuso Intima Just outside granulosa secretory cell—testoerone (stimulated by LH) granulosa cells estradiolo externa contractile outside follicle function in ovulation- secondary follicles and atresiao mature follicle filled with fluido fluid in antrum growth factor plasminogen—anticoagulant fibrin—coagulant steroidso atresia apoptosis of primary follicle- fisorganized antrum- corona radiate disintegrated- oogenesiso see slide for process and imageso start in meiosis I and stop primary oocyte (born with) secretion of H-AP hormones secondary oocyte recruited primordial only one decelopmento meiosis only finishes if fertilizedo born with all eggs then released once a month after puberty begins- ovulationo see slide for process and imageso estradiol negative feedback on LHo 48 hours before changes to positive feedbacko Increase estradiol increased LH leads to ovulation- Corpus luteumo Progesterone secretion regulated by LHo Without pregnancy—apoptosis Corpus albicanso With pregnancy—embryonic thromboblasts secrete HCG to stimulate progesterone secretion from corpus luteum for 4-5 months- Uterine (fallopian) tubeso Peg cells Secrete sperm activating factors Capacitation factor Sperm need to be exposed to be able to fertilize ovum- In distal third When fertilized- Stimulated to finish meiosis 2o Divides very rapidly forming clustero Blastocye moves into uterus Stem cells are completely identical- zygote then coaxed by
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