Campbell s Biology 9e Reece et al Chapter 12 The Cell Cycle In this chapter 24 questions are new and 12 have been altered to incorporate new material from the textbook As in the other chapters any questions that depend on figures or introductory scenarios have been placed at the end of the chapter rather than in concept sequence Multiple Choice Questions 1 The centromere is a region in which A chromatids remain attached to one another until anaphase B metaphase chromosomes become aligned at the metaphase plate C chromosomes are grouped during telophase D the nucleus is located prior to mitosis E new spindle microtubules form at either end Answer A Topic Concept 12 1 Skill Knowledge Comprehension 2 Starting with a fertilized egg zygote a series of five cell divisions would produce an early embryo with how many cells A 4 B 8 C 16 D 32 E 64 Answer D Topic Concept 12 1 Skill Application Analysis 3 If there are 20 chromatids in a cell how many centromeres are there A 10 B 20 C 30 D 40 E 80 Answer A Topic Concept 12 1 Skill Application Analysis 1 Copyright 2011 Pearson Education Inc 4 For a newly evolving protist what would be the advantage of using eukaryote like cell division rather than binary fission A Binary fission would not allow for the formation of new organisms B Cell division would allow for the orderly and efficient segregation of multiple linear chromosomes C Cell division would be faster than binary fission D Cell division allows for lower rates of error per chromosome replication E Binary fission would not allow the organism to have complex cells Answer B Topic Concept 12 1 Skill Synthesis Evaluation 5 Suppose a biologist can separate one of a dozen pieces of chromatin from a eukaryotic animal nucleus It might consist of which of the following A one twelfth of the genes of the organism B two chromosomes each with six chromatids C a single circular piece of DNA D two long strands of DNA plus proteins E two chromatids attached together at a centromere Answer D Topic Concept 12 1 Skill Knowledge Comprehension 6 At which phase are centrioles beginning to move apart in animal cells A telophase B anaphase C prometaphase D metaphase E prophase Answer E Topic Concept 12 2 Skill Knowledge Comprehension 7 If cells in the process of dividing are subjected to colchicine a drug that interferes with the formation of the spindle apparatus at which stage will mitosis be arrested A anaphase B prophase C telophase D metaphase E interphase Answer D Topic Concept 12 2 Skill Application Analysis 2 Copyright 2011 Pearson Education Inc 8 If there are 20 centromeres in a cell at anaphase how many chromosomes are there in each daughter cell following cytokinesis A 10 B 20 C 30 D 40 E 80 Answer A Topic Concept 12 2 Skill Application Analysis 9 Where do the microtubules of the spindle originate during mitosis in both plant and animal cells A centromere B centrosome C centriole D chromatid E kinetochore Answer B Topic Concept 12 2 Skill Knowledge Comprehension 10 Taxol is an anticancer drug extracted from the Pacific yew tree In animal cells Taxol disrupts microtubule formation by binding to microtubules and accelerating their assembly from the protein precursor tubulin Surprisingly this stops mitosis Specifically Taxol must affect A the formation of the mitotic spindle B anaphase C formation of the centrioles D chromatid assembly E the S phase of the cell cycle Answer A Topic Concept 12 2 Skill Application Analysis 11 Which of the following are primarily responsible for cytokinesis in plant cells but not in animal cells A kinetochores B Golgi derived vesicles C actin and myosin D centrioles and centromeres E cyclin dependent kinases Answer B Topic Concept 12 2 Skill Knowledge Comprehension 3 Copyright 2011 Pearson Education Inc 12 In which group of eukaryotic organisms does the nuclear envelope remain intact during mitosis A seedless plants B dinoflagellates C diatoms D dinoflagellates and diatoms only E seedless plants dinoflagellates and diatoms Answer D Topic Concept 12 2 Skill Knowledge Comprehension 13 Movement of the chromosomes during anaphase would be most affected by a drug that A reduces cyclin concentrations B increases cyclin concentrations C prevents elongation of microtubules D prevents shortening of microtubules E prevents attachment of the microtubules to the kinetochore Answer D Topic Concept 12 2 Skill Synthesis Evaluation 14 Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus The measured DNA levels ranged from 3 to 6 picograms per nucleus In which stage of the cell cycle did the nucleus contain 6 picograms of DNA A G0 B G1 C S D G2 E M Answer D Topic Concept 12 2 Skill Application Analysis 15 A group of cells is assayed for DNA content immediately following mitosis and is found to have an average of 8 picograms of DNA per nucleus How many picograms would be found at the end of S and the end of G2 A 8 8 B 8 16 C 16 8 D 16 16 E 12 16 Answer D Topic Concept 12 2 Skill Application Analysis 4 Copyright 2011 Pearson Education Inc 16 For anaphase to begin which of the following must occur A Chromatids must lose their kinetochores B Cohesin must attach the sister chromatids to each other C Cohesin must be cleaved enzymatically D Kinetochores must attach to the metaphase plate E Spindle microtubules must begin to depolymerize Answer C Topic Concept 12 2 Skill Synthesis Evaluation 17 Why do chromosomes coil during mitosis A to increase their potential energy B to allow the chromosomes to move without becoming entangled and breaking C to allow the chromosomes to fit within the nuclear envelope D to allow the sister chromatids to remain attached E to provide for the structure of the centromere Answer B Topic Concept 12 2 Skill Synthesis Evaluation 18 Which of the following best describes how chromosomes move toward the poles of the spindle during mitosis A The chromosomes are reeled in by the contraction of spindle microtubules B Motor proteins of the kinetochores move the chromosomes along the spindle microtubules C Nonkinetochore spindle fibers serve to push chromosomes in the direction of the poles D The chromosomes are reeled in by the contraction of spindle microtubules and motor proteins of the kinetochores move the chromosomes along the spindle microtubules E The chromosomes are reeled in by the contraction of spindle microtubules motor proteins of the kinetochores move the chromosomes along the spindle microtubules and