Psyc4130 1nd Edition Lecture 7 Outline of Last Lecture II. Overview/Review of Neuroanatomy III. Major Neurotransmittersa. Monoaminesi. Dopamineii. Norepinephrineiii. Serotoninb. Otheri. Acetylcholineii. Glutamateiii. GABAOutline of Current Lecture IV. DopamineA. Substantia NigraB. VTAV. Roles of DopamineA. MotorB. MotivationVI. NorepinephrineA. Locus coeruleusVII. Serotonin A. Raphe nucleiCurrent Lecture[Test ch 1-2: without neuroanatomy stuff]- TyrosineDOPA (main therapy for parkinson’s) Dopamine Norepinephrine (locus coeruleus) Epinephrine 1. Dopamine- Two major sources of dopamine in the brain-o Both found in midbrain- A. Substantia Nigra (SN): o MotorThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.o Clusters of nuclei in midbrain, houses cells of dopamine (means black area/body). o Dopamine producing neurons into area of brain called DORSAL STRIATUM (dorsal= top part). Parkinson’s is a dopamine deficiency o Pathway is called nigrostriatal - B. VTA: o Motivationo Pathway is called mesolimbico Ventral Striatum/Nucleus accumbens (where dopamine is being released- NAc) Roles of Dopamine-- A. Motor: dopamine translate the command signals that originate in motor areas of brain and causes results of skeletal muscular movement (without dopamine we wouldn’tbe able to move our bodies, we would freeze up)- B. Motivation: the actual drive, craving, desire, pursuit. o Dopamine has to do with: Positive: applies stimulus Negative: removes stimulus - Neg reinforcement- take away something unpleasant- Neg punishment- take away something good Reinforcement: increases the frequency of desirable behavior Punishment: decreases the frequency of undesirable behavior- Addictive behaviors: porn, gambling, gaming, sex, exerciseo Has everything to do with dopamineso Fixation, motivating all your time towards one thing 2. Norepinephrine (NE)- Locus coeruleus: where you find cell bodies of norepinephrine releasing neurons o Major roles of norepinephrine: attention, how much do I need to be paying attention to my environment? Helps enable short term memory so you can absorb stuff that’s important to youo Sends axons down the spinal cordo Attention, alerting, vigilance, (extreme- during fight or flight= panic because of sleep deprivation, stress, and Adderall) o Attention deficit hyperactivity disorder 3. Serotonin (5-HT)-Raphe nucleio Send serotonin to all areas of brain and down to spinal cordo Mood ~ affecto Affect regulation- regulating your mood (tied in with serotonin levels) People who struggle with this tend to have low serotonin levelso Sleep cycles dependent on serotonin (melatonin)o Impulsive
View Full Document
Unlocking...