BIOL 1107 1nd Edition Lecture 25 Outline of Last Lecture I Genetically Modified Organisms GMOs II Bio farming III Plasmids Restriction Enzymes Outline of Current Lecture I Mitosis II Chromosome Mapping III Karyotype IV Interphase V Phases of Mitosis Current Lecture I Mitosis Why do cells divide Repair growth Every 2 weeks you have new skin layer your liver regenerates every 1 2 years What doesn t divide Brain cells Dividing cells can be bad cancerous Eukaryotic chromatin packing These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute II Chromosome mapping III 23 pairs of chromosomes 46 chromosomes Q The diploid chromosome in standard lab mice genus Mice is 40 what is n for this organism n 20 n pairs of chromosomes Karyotype x y male x x female 46 or n 23 n in humans IV Interphase What would you expect the chromosome to look like in G1 2 arms What would you expect the chromosome to look like in G2 For Test 4 you should be able to draw a chromosome in different phases Also you should be able to tell what phase something s in by looking picture During interphase centrosomes replicate centrioles made up of microtubules centrioles are very important Without microtubules spindle won t be able to form properly V Phases of Mitosis 1st phase of mitosis prophase o Chromosome condense packaging gets more and more and more mitotic spindle forming asters Prometaphase nuclear envelope breaks down spindle binds chromosomes kinetochore Anaphase sister chromatids separate get pulled to opposite sides now daughter chromosomes Telophase cytokinesis nuclear envelope reforms chromosomes decondense cell uses actin and squeezes it in
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