BIOL 1107 1nd Edition Lecture 16 Outline of Last Lecture I CR Stage 3 Citric Acid cycle Krebs II CR Stage 4 Oxidation Phosphorylation III Regulation of Cellular Respiration process Outline of Current Lecture I Fermentation Process II Why Anaerobic Respiration in Humans III Extra Credit Cyanide vs DNP Current Lecture I Fermentation Process What is the main purpose of fermentation Regenerate NAD also so that we can keep making ATP What stage benefits from fermentation Glycolysis Why not the other stages FAD also needed for Krebs NOT enough These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute II Why Anaerobic Respiration in Humans Supply of energy in muscle ATP 2 3 sec Creatine P III The phosphate of Creatine goes to ADP makes ATP substrate level phosphorylation 10 12 sec Glycogen aerobic and anaerobic Aerobic gives us about 60 minutes worth of energy anaerobic only 1 2 mins shows us the importance of oxygen Examples quick sprint anaerobic carbs enter pathway glycolysis while lipids enter pathway only at Krebs cycle high intensity both anaerobic and aerobic carbs fats moderate pace aerobic carbs fats Extra Credit Cyanide vs DNP Make sure to review the key aspects discussed in the extra credit assignment below Cyanide ion prevents transport of electrons cytochrome C to oxygen affects oxidative phosphorylation stage DNP in living cells it acts as a proton ionophore an agent that can shuttle protons hydrogen cations across biological membrane also affects oxidative phosphorylation stage Some questions to consider during your discussion o What stage of cellular respiration does these compounds affect o Can you draw a diagram showing the target of each compound and its immediate effects o What cellular metabolites should be measured ATP NAD NADH O2 H glucose pyruvate
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