BIOSC 150 1nd Edition Lecture 24 Outline of Last Lecture I Genetics of Cardiomyopathy II Crossing over Outline of Current Lecture 1 Genetics Vs Genomics Current Lecture A genome is composed of 3 billion nucleotides times 2 Most DNA is not protein coded Fewer genes on the Y chromosome as compared to the X chromosome Y chromosome responsible for maleness Average chromosome has 1 000 genes The X chromosome doesn t relate to sex or gender X chromosome does relate to sex linked disease These phenotypes are only displayed in males How you know the disease is coming from the X chromosome One out of every 1000 nucleotides are different Most DNA is not genes Genetics sequence specific genes for mutation known to cause specific disease can be associated with the risk of disease Genomic looks through your whole genome and tries to figure out everything it can tell us sequencing everything Most differences among humans are single nucleotide polymorphisms SNP for instance it would be a deletion or replication of the nucleotide Four flavors possible at any given position These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute SNP studies research a particular phenotype then look for SNP s over the genome Crossing over is rare between genes that are close it usually occurs between genes that are far apart take place during Meiosis I
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