BIosc 150 1nd Edition Lecture 4Outline of Last Lecture I. Nucleic AcidsOutline of Current Lecture II. ProteinA. Structure is equivalent to functionIII. Hemoglobin and its jobCurrent Lecture-Protein structure determines the function-Proteins build from prime 1 through prime 3 structures-As researchers, we study proteins to figure out human diseases such as sickle cell caused by hemoglobin-In order to determine a protein’s mass, one would need to unfold the protein down to its polypeptide chain – (denaturants unfold proteins)Detergent- hides hydrophobic groups (so water doesn’t push it back together)-It is known that the structure of a protein is essential because if the protein is unfolded it cannot perform the same function-Protein structure and function is diverse-Enzymes contain “active site” clefts – this is where substrates are bonded and its job is done-Enzymes change shapes when binding substratesHemoglobin- a protein that transports oxygen-Hemoglobin is composed of 4 polypeptides coded for by 2 DNA genesThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a
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