BIOSC 150 1nd Edition Lecture 14Outline of Last Lecture I. Subcellular structures continuedII. SignalsOutline of Current Lecture 1. Tissues2. Organs3. Muscle4. Transmembrane functionsCurrent Lecture-Cells do not exist in isolationTissue- an assemblage of cells that function as a unitOrgan- unit comprised of multiple tissues-Cells are supported by extracellular matrix (ECM)-The main fibrous component of ECM is collagen, which resists tension!-Proteoglycans contribute to the ground substance in which fibers are embedded-Glycoproteins also contribute to ground substanceIntegrins- link the cytoskeleton to the ECM-Epithelial tissues act as regulated barriersTight Junctions- tightly pack epithelial cells, act as great barriers, and help polarize the celssDesmosomes- epithelial sheets that resist tensile forces (adhesion)-Transmembrane cadherins mediate homotypic adhesionGap Junctions- control communication in epithelial cellsThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.-Epithelia generate a minimal amount of ECM; the basal laminaBasal Lamina- supports epithelium, flitration/selective binding, and maintains cell polarityHemidesmosomes- may anchor an epithelium to the basal lamina-Connective Tissues are not tightly packed and do not contain tight junctions or desmosomes; they are however highly vascularized-Connective Tissues underlies epithelia in skin and mucosal tissues – it forms ligaments and tendonsAdipose tissue- used for energy storage, cushioning, and warmth-Skeletal muscle striations reflect sarcomere architectureCardiac Muscles- involuntary, branched cell with a single nucleus, striated, and connected by intercalated
View Full Document
Unlocking...