BIO 150 1nd Edition Lecture 22 Outline of Last Lecture I. Case StudyII. Genetics of CardiomyopathyOutline of Current Lecture II. Genetics of Cardiomyopathy Current Lecture-Mendel studied 2 distinct phenotypes ‘flavors’ (alleles)-Each trait was controlled by 1 gene-Most traits controlled by more than one geneMeiosis-DNA replication occurs before meiosis takes place1. Homologous chromosomes pair2. Crossing over – paired their crossing over (spindle elongated)3. Microtubules capture chromosomes (first arrange on equator)4. Sisters still together – homologue go to separate poles5. Another mitotic division, elongated, no spindle6. Spindle forming7. Sisters align at the equator8. Chromosomes separate 9. Form new nuclear envelopeThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.-Recombination creates new allele combinations-Parental chromosomes replicate (sisters)-New combination showed genes of same chromosome could be separated onto different chromosomes -Ratios of R and Y are assorting independently-F2 phenotype ratio changed and F1 phenotypes stayed the
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