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MSU MMG 451 - MMG 451 Chapter 11

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Chapter 11: Differentiation and Functions of CD8+ Effector T Cells (and NK cells – Chapter 4) Please recall that CTLs are useful in the protection against viral infections, but they are also pivotal to protection against intracellular bacterial infections such as Mycobacterium tuberculosis, and tumors (which will be discussed later in the semester). Activation of naive CD8+ T cells and their effector functions: Abbas, Lichtman and Pillai8_Figure 11-1; p.232How can helper T cells assist in CD8+ T cell differentiation? Abbas, Lichtman and Pillai8_Figure 11-2; p.233Cell-Mediated Cytotoxicity Abbas, Lichtman and Pillai8_Figure 11-4; p.235Abbas, Lichtman and Pillai8_Figure 11-6; p.237How do NK cells compare to CTLs? Abbas, Lichtman and Pillai8_Figure 4-7; p.65NK Cell Inhibitory and Activating Receptors Abbas, Lichtman and Pillai8_Figure 4-8;


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MSU MMG 451 - MMG 451 Chapter 11

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