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MSU MMG 451 - MMG 451 Chapter 10

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Chapter 10: Differentiation and Functions of CD4+ Effector T Cells Please recall from previous chapters there are 2 major classifications of T cells: helper T cells (Th cells, or CD4+ T cells) and cytotoxic T cells (CTLs, or CD8+ T cells). In this chapter we will look into the different subsets of CD4+ T cells. Cell-Mediated Immunity Abbas, Lichtman and Pillai8_Figure 10-1; p.214CD4+ T Cell Responses Abbas, Lichtman and Pillai8_Figure 10-2; p.215The Subsets of CD4+ T Cells Th1 Cells Abbas, Lichtman and Pillai8_Figure 10-4; p.217 Abbas, Lichtman and Pillai8_Figure 10-5; p.219What can Th1 cells do? IFN-γ – Macrophage Activation Abbas, Lichtman and Pillai8_Figure 10-6; p.220 Abbas, Lichtman and Pillai8_Figure 10-7; p.221Th2 Cells Abbas, Lichtman and Pillai8_Figure 10-7; p.221 Abbas, Lichtman and Pillai8_Figure 10-8; p.222Functions of Th2 Cells IL-4 – IL-5 – IL-13 – Abbas, Lichtman and Pillai8_Figure 10-9; p.223Th17 Cells Abbas, Lichtman and Pillai8_Figure 10-10; p.225 Abbas, Lichtman and Pillai8_Figure 10-11; p.226Functions of Th17 Cells IL-17- TNF – IL-22 – IL-21 – Abbas, Lichtman and Pillai8_Figure 10-12;


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