BMS 300 1st edition Lecture 7 Outline of Last Lecture I. Mitochondria and the cytoskeleton-mitochondria 1. structure2. function -use O2 to generate ATP—Oxidative phosphorylation3. history of the mitochondria -capture-genetic lining -the cytoskeleton 1. protein polymers with protection ability 2. microtubules-polymers of tubulin 3. filament actin-polymer of G-actin 4. intermediate of filament proteins II. Microtubules structure -tubulin assembly -polarity of molecules -microtubules as substrate for movement 1. kinesin-structure-ATPase -motor function -dynein -actin using myosinThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.Outline of Current Lecture I. Filamentous actin in the cortical cytoskeleton-myosin motors 1. 2. movement in F-actin -vesicle access to the membranes1. local delivery II. DNA structure, replication, and the central dogma -DNA as molecules of life 1. stores information about RNA structures 2. RNA structure stores information about protein structure III. DNA components -5carbon sugar dextrose -bases 1. purines >adenine>quinine 2. pyrimidines >thymine >cytosine IV. Polymerization of sugars -phosphodiester bondsV. Antiparallel structure and hydrogen bonds -role of bases VI. Replication Current LectureFilamentous Actin as a Substrate for Vesicular Transport -there is an actin binding site -there is an ATP binding site where adenosine and triphosphate turn into ATPase**see image—hard to explain with words hereLong Distance vs. Short Distance Transport & Vesicle access to the plasma membrane -there is a cortical actin -kinesin -microtubules -all of these are long distance -the SNARE hypothesis is that the vesicle and targets both SNARE and release contents **see image Exocytosis: the process of squishing the two membranes together Endocytosis: claythrinDeoxyribonucleic Acid -stores information -replication -changes by mutation Central Dogma: where the DNA stores information -the information stored in DNA is transferred to RNA which is ribonucleic acid -the RNA is transferred to protein -information is stored as a sequence of nitrogenous bases -information is stored as a sequence of bases in RNA is transported into the sequence of proteins Components of DNA -Deoxyribose 5-carbon sugar -the only difference between deoxyribose and ribose is that they change
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