BMS 300 1st Edition Lecture 13 Outline of Last Lecture I. Cell junctioning in epithelia-anchoring 1. hemidesosomes-basal lamina-integrin 2. desmosomes-cell to cell-cadherin -occluding 1. tight -communicating- GAP 1. connexons composed of 6 connexins II. Glandular epithelium-exocrine/duct gland -surface -duct-secretory -adenocarcinoma III. Connective tissue—scattered cells connected by the extracellular matrix they secrete-connective tissue proper 1. fibrocytes -cartilage 1. chondrocytes These notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.-bone 1. osteocytes -blood1. hematopoietic stem cells IV. Skin as an organ -epidermis Outline of Current Lecture V. Cells of mesenchymal origin -fibrocytes 1. CTP (connective tissue paper) -chondrocytes 1. cartilage -osteocytes (secrete calcium phosphate) 1. bone -hematopoietic stem cell 1. blood VI. Extracellular proteins of connective tissue -collagenrope like -elastinstretchy -glycosaminoglycanglass and epoxy like VII. Skin as an organ -epithelium 1. epidermis-connective tissue proper 1. dermis VIII. Organization of epidermis -stratified squamous epithelium -keratinocytes -melanocytes IX. Organization of the dermis -CTP1. fibrocytes 2. extracellular proteinsCurrent LectureConnective tissues are composed of scattered cells embedded in the protein matrix they secrete -Fibrocytes: CTP >tendons, ligaments, dermis -Chondrocytes: >elastic (ear) >fibrocartilage (knee) >hyaline cartilage (fiberglass) –fills in spaces Skin-is an organ composed of an epithelium on a layer of connective tissue Epithelium: stratified squamous epithelium composed of keratinocytes Connective tissue: CTP=dermis >fibrocytes-extracellular proteins-only two layers are really alive= SS and SBScar: lumps of extracellular proteins Henna: binds to keratin Tattoo: dyes proteins and fibrocytes in the dermis-migration caused melanin mutations to alter skin by the amount of melanin that melanocytes secrete Melanocytes: secrete pigment called melanin which is taken up by keratinocytes called tyrosineAppendages of Skin **see
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