MIC 205 1st Edition Lecture 24Outline of Last LectureI. Microbial Diseasesa. Bacterial-Skin Cont.b. Viral-Skin Outline of Current Lecture II. Microbial Diseasesa. Viral-Skin Cont.Current Lecture - Small Pox as a Biological Warfare Agent o Spreads quickly from person to person (indirect contact)o U.S. reinstated vaccine routines for military o Progression of other diseases makes early recognition difficult - Smallpox vs. Chickenpoxo Small Pox 2-3 days severe illness before rash Mouth and face first Develop at once and look the same all over Change slowly and scab over 9-15 days Rash on hands, feet, face Firm, dome-shaped and DEEP in skino Chickenpox 0-2 day mild onset of illness before rash Face and trunk first Develop in crops Come and are gone over 24 hrs Typically stay on the trunk (torso) Superficial pustules like water droplets (NOT DEEP)- Chickenpox and Shingleso Varicellovirus caused (dsDNA virus)o Respiratory tract entryo Rasho 2-3 week incubationo Prevention through vaccineThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute. Virus can go LATENT-> can be reactivated and cause Shingles as an adult - Immunodeficiency Diseaseso Some infections associated with acquired immunodeficiency syndrome (AIDS) manifest on the skin Shingles, herpes, Kaposi’s sarcoma- Herpes Infectionso Signs/Symptoms: Slowly spreading skin lesions (cold sores, canker sores)- Reoccurring lesions due to activation of latent viruso Diagnosis/Treatment: Immunoassay reveals presence of viral antigens- HHV-1 (cold sores)- HHV-2 (genital herpes)- Warts (viral infection)o Human papillomaviruses (HPV)o Localized infectiono New warts develop due to latent viruses Latent HPV van lead to cervical cancer in women - Gardasil vaccine (Merck) immunity to 70% of cervical cancers and 90% of genital warts- Parasitic Infestations of the Skino Leishmaniasis (Protozoan caused) 3 clinical forms 1. cutaneous- large painless lesions on skin2. mucocutaneous- skin lesions enlarge to include the mucous membranes (mouth, nose, throat)3. visceral- spreads through macrophages (liver, spleen, bone marrow) Caused by Endemic to regions of the tropics, subtropics and middle east o Scabies Tiny insects lead to intense itching- Burrow into skin and eat the tissueo Cause rash Mite called Sarcoptes scabiei Transmission by prolonged bodily contact (sex)- Clothes, towels, etc.Clicker questions:One of these diseases in caused by a type of pathogen that is different from the type of pathogen that causes all the othersa) Varicellab) Leishmaniasis (protozoan caused)c) Measlesd) Wartse) Hand foot mouth diseaseWhich is the most appropriate way to address the severe pain caused with shingles?a) Dress rash with tight bandagesb) Inject anti inflammatory meds to the spine region through an epiduralc) Coat rash with anti bacterial creamd) Vaccinate patient with chickenpox vaccinee) Lance the pustular lesions to drain
View Full Document
Unlocking...