- MIC 205 1st Edition Lecture 23Outline of Last LectureI. Microbial Diseasesa. Skin Outline of Current Lecture II. Microbial Diseasesa. Bacterial-Skin Cont.b. Viral-SkinCurrent Lecture o Pseudomonas Infection Caused by P. aeruginosa, shown by green pigment (pyocyanin)- Found in soil Virulence factors: adhesins, toxins, polysaccharide capsule Found in: - BURN victims Pyocyanin discoloration = massive infection Treatment:- Resistant to drugs o Cutaneous Anthrax Caused by Bacillus anthacis (spore forming)- From direct skin contact Symptoms: lesion that forms an eschar, black scab - Immediate response Treatment: ciprofloxacino Gas Gangrene Caused by Clostridium species (endospore forming) (Clostridium perfringens)- Enters dead (necrotic) tissue from trauma Symptoms: crackling sounds, bubbles, foul smelling drainage Surgical removal of tissuesThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.Clicker Question #1:Which of the following bacterial diseases of the skin is associated with gram positive cocci that grow in grape like clustersa) Erysipelasb) Scalded skin syndromec) Necrotizing fasciitisd) A and Be) A, B, C ANSWER: D) **staph caused disease C) is caused by Streptococcus Clicker Question #2:Which of the following bacteria can cause massive infections that are characterized by fever, chills, sepsis, foul smelling tissue necroses?a) Clostridium perfringensb) Pseudomonas aeruginosac) Streptococcus pyogenesd) Bacillus anthracise) Staphylococcus aureusAnswer: A) Gas gangrene is caused by a) Clostridium perfringensViral Diseases of the Skin:- Not localized, but signs and symptoms are expressed on the skino Measles (Rubeola) Single stranded RNA virus - Caused by Morbillivirus o Viral proteins cause infected host to fuse to neighboring cells- By inhalation of viral particles- Signs/ symptoms: progressive fever, malaiseo Koplik’s spots in moutho Red, raised body lesions- Prevention: MMR vaccine (measles, mumps, rubella)o Rubella- don’t have Koplik spotso Rubeola (red measles)- have Koplik spotso Smallpox Caused by Orthopoxvirus (variola virus)- By inhalation Signs/symp: severe rash that becomes papules, vesicles, and then pustules Prevented by a vaccine that was discontinued in US in 1972 1st human disease that is eradicated Progresses in
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