MBIOS 101 1nd Edition Lecture 31 Outline of Last Lecture - Lines of Defense1. Overview of third line of defense 2. Types of Blood3. Five classifications of immunoglobulin Outline of Current Lecture – 1. IgG – found response and rh factor2. IgA – mucous 3. IgD – B-cells 4. IgE –allergy Current Lecture – First Line of Defense1. Hormonal response a. Five types of immunoglobin i. IgG1. Functionsa. Second response b. Find in milkc. Rh factor 2. Rh factor – another factor on the surface of blood cells a. Can be rh negative or positive b. Genetic c. Placenta Example: i. Father – positive ii. Mother – negativeiii. Baby – positiveiv. When lining in uterus pulls away from wall mom and baby blood mixv. Mother’s blood makes antigens against rh positive vi. Second, third, fourth, etc. mothers blood crosses over and destroys the baby’ blood ii. IgA – 1. Produced by cells in mucous membranes 2. Protect us by this mucous membrane These notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.iii. IgD1. Can sit on the surface of a b-cell/basophil 2. Cell surface immunoglobulin (IgM or IgD)3. Replicates and primes other cells surfaces so they make antigens iv. IgE1. Allergic reaction2. Works against parasites3. Parasites –a. IgE antibodies attack parasite b. Shots in lytic enzymes 4. Allergiesa. IgE antibodies sit on MAST cells readyb. When is meets an allergen is becomes leaky causing runny eyes, nose etc c. Also can result in welts 5. Can get blood allergy tests v. Antibody marking an antibody for destruction vi. Antibodies mark and immobilize and then macrophages and neutrophils can eat
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