MBIOS 101 1nd Edition Lecture 23 Outline of Last Lecture - Lines of Defense1. First line a. Eyesb. Earsc. Nasal passage 2. Second3. Third Outline of Current Lecture – 1. Eyes2. Ears3. Nasal Passage4. Lungs5. Skin Current Lecture 1. First Line of Defensea. Eyesb. Earsc. Nasal Passagesi. Nose hairii. Breathing iii. Mucus –1. Produced by Golbert cells 2. Vitamin A – needed to keep epithelial cells healthy These notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.iv. Cilia – sweeping motion prevents organisms from attaching (if the organism attaches then it traps it)1. In nasal passages – not just nose2. Traps particulate matter – do not want this matter down in the lungs 3. Sneezing – removes particulate matter 4. Normal Flora Organism (protect their home) 5. MAST – Cells a. Allergy b. Runny nose and eyesc. Histamines – causes your eye and nose to try to flush out the matter d. Happens when your body is allergic to something e. Benadryl- antihistamines: stops reaction d. Lungs – Bronchi and Trachea i. Mucus and cilia are used to protect ii. What if something does get down into the lungs?1. Alvedar – macrophages (cells) that can clean up by eating matter iii. Pharynx and Epiglottis e. Skin – largest organ of the body/tough i. Low temperature – leprosy likes lower temperature and so loves the temperature of skin/ in general lower temperature protects skin ii. pH of skin is more acidic iii. NFO – bacteria, mold, and fungi (different in different spots of the body) iv. Sweat – 1. Water and NaCl (salt follows water and vice versa) keeps you cooler2. Lysozyme – in sweat and kills transient organisms 3. Zinc and Iron v. Sebacceous glands -- Produces oil 1. Lubrication2. Luster – don’t want skin to crack 3. Lysozyme vi. Antibacterial soaps and hand sanitizers – not necessary really good for you 1. Need some dirt to be healthy – stimulates and educates your immune response 2. Some chemicals in these soaps are carcinogenic vii. Skin is thick 1. Skin is always replacing itself viii. As you age1. Skin is not as thick2. Not as elasticix. Layers of Skin1. Epidermis2. Dermis3. Subcutaneous tissue – fat layerx. Hair follicles register information – touch, pain, motionxi. Rivets in skin - Protectionxii. Nerve endings in skin send you informationxiii. Lymphatic vessels take away fluid xiv. Skin mites –
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