Berkeley BIOLOGY 1B - Lecture Notes (9 pages)

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Lecture Notes



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Lecture Notes

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Lecture Notes


Pages:
9
School:
University of California, Berkeley
Course:
Biology 1b - General Biology
General Biology Documents

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Bio 1B Lecture Outline please print and bring along Fall 2008 B D Mishler Dept of Integrative Biology 2 6810 bmishler berkeley edu Evolution lecture 11 Hardy Weinberg departures genetic variation drift Dec 1st 2008 475 479 ch 23 in 8th ed 459 464 ch 23 in 7th ed Genetic variation genetic drift summary of topics Extent of genetic variation in natural populations Examine the extent of genetic variation in natural populations and understand the concepts of the neutral balancing selection and evolutionary lag schools to explain this variation Deviations from Hardy Weinberg HW Explain the consequences of violating each of the assumptions of the HW law non random mating mutation migration and genetic drift selection is for next lecture Genetic drift Understand the short and long term effects of genetic drift on the genetic structure of populations and the consequences of founder effects and bottlenecks Sexual versus asexual reproduction Contrast sexual and asexual reproduction in terms of the generation of genetic variability Extent of genetic variation in natural populations How much genetic variation is there in natural populations Before 1966 there were two disparate views on the extent of overall genetic variation in natural populations classical and balance The classical view assumes that at nearly every locus every individual is homozygous for a wildtype allele In addition each individual is heterozygous for rare deleterious alleles and occasionally heterozygous for a selected allele maintained in the population by balancing selection The balance view in its extreme form on the other hand assumed that there was a lot of genetic variation in populations so that most individuals will be heterozygous for alternative alleles at very many of their loci This genetic variation was believed to be maintained by some form of balancing selection Evolution 11 pg 1 The year 1966 is important in population genetics as it marks the use of an objective test to measure the extent of



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