BIOL 101 1nd Edition Lecture 33 Outline of Last Lecture I Innate Immune Response a External Barriers b Internal Barriers II Inflammatory Response III Adaptive Immunity s Two Arms IV Antibody mediated Response Outline of Current Lecture I Cell Mediated Adaptive Response II Cytotoxic T Cells III Self Nonself Complex Current Lecture V Cell Mediated Adaptive Response These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute Cytotoxic T cells are able to recognize infected body cells because the green protein and the yellow triangles form a self nonself complex The Cytotoxic T cells are the cells with the purple proteins The red circles go into the holes and lysis the cell these enzymes call the cell death Yellow macrophage big eater he eats the pathogens The macrophage can present the self nonself protein since it shows antigens as well The second cell is a helper T cell middle cell it recognizes the self nonself complex The blue cell is a white blood cell known as a B cell The helper T cells stimulate the growth of the B cell The B cells produce antibodies The cell on the bottom is a cytotoxic T cell The consequence of having no helper T cells you wouldn t be able to stimulate B cells therefore you wouldn t produce antibodies this occurs in HIV infected patients As the HIV levels in blood increases the number of Helper T cells decreases diminishing the patient s ability to fight infection When helper T cells are low enough the body cannot fight disease and dies
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