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UNC-Chapel Hill BIOL 101 - Pedigrees

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BIOL 101 1nd Edition Lecture 17 Outline of Last Lecture I. DNA Structure and FunctionII. Three teamsIII. The Race to Find DNAIV. Current LectureOutline of Current LectureI. Hershey Chase ExperimentsII. PedigreesCurrent LectureHershey Chase ExperimentsDNA or Protein?-phage – consists only of DNA and proteinsphage – genetic material is injected into bacteria cell assembles back up and then the cell lysisRadioactive phosphorus labels the DNA nitrogen base PedigreeA pedigree is a diagram of family relationships that uses symbols to represent people and lines to represent genetic relationships. These diagrams make it easier to visualize relationships within families, particularly large extended families. Pedigrees are often used to determine the mode of inheritance (dominant, recessive, etc.) of genetic diseases. A sample pedigree is below.These notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.In a pedigree, squares represent males and circles represent females. Horizontal lines connecting a male and female represent mating. Vertical lines extending downward from a couple represent their children. Subsequent generations are therefore written underneaththe parental generations and the oldest individuals are found at the top of the pedigree.If the purpose of a pedigree is to analyze the pattern of inheritance of a particular trait, it is customary to shade in the symbol of all individuals that possess this trait.In the pedigree above, the grandparents had two children, a son and a daughter. The son had the trait in question. One of his four children also had the trait.In the exercises below, assume that the trait in question is a genetic disease or abnormality. We will learn patterns of inheritance that have the following modes of inheritance:autosomal dominantautosomal recessiveX-linked


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UNC-Chapel Hill BIOL 101 - Pedigrees

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