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UNC-Chapel Hill BIOL 101 - The Flow of Genetic Information

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BIOL 101 1nd Edition Lecture 18 Outline of Last Lecture I. Hershey Chase ExperimentsII. PedigreesOutline of Current Lecture I. The Flow of Genetic InformationII. Act I: ReplicationIII. Act II: Transcription and TranslationCurrent LectureThe Flow of Genetic InformationClass discussionToday in class we are going to role-play the flow of genetic information. We will think first abouttranscription and then about translation. There will be many members of the cast involved in each act of our play today. Put on your thinking caps because you will either be participating as adirector or on stage as a cast member!I. Act I: Replication:i. The Cast – we know they are DNA bc they have CGATDeoxyribonucleotidesnucleausDNA polymerase – enzyme that synthesized DNA polymers ii. The Script – all of replication occurs in the nucleusAll of the genes are not coding for proteins so they different colors could be the introns and exonsThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.Took our DNA, separated our strand to make a parent strand. Then the DNA polymerase came in a paired up with the parent strand by Chargoffs rules creating an identical daughter strand. II. Act II: Transcription and Translation: i. The CastDNA, RNA, extrons, introns, nucleus, the RNA polymerase synthesizes the mRNA – this all occurs in the nucleus. Anticodon tRNA has an amino acid and an anticodonii. The ScriptCap and tail protect from enzymatic degradationTake away introns Move to the ribosomeOccurs in the cytoplasm at a ribosome You can have mutations within


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UNC-Chapel Hill BIOL 101 - The Flow of Genetic Information

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