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UNC-Chapel Hill BIOL 101 - Pedigrees

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BIOL 101 1nd Edition Lecture 17 Outline of Last Lecture I DNA Structure and Function II Three teams III The Race to Find DNA IV Current Lecture Outline of Current Lecture I II Hershey Chase Experiments Pedigrees Current Lecture Hershey Chase Experiments DNA or Protein phage consists only of DNA and proteins phage genetic material is injected into bacteria cell assembles back up and then the cell lysis Radioactive phosphorus labels the DNA nitrogen base Pedigree A pedigree is a diagram of family relationships that uses symbols to represent people and lines to represent genetic relationships These diagrams make it easier to visualize relationships within families particularly large extended families Pedigrees are often used to determine the mode of inheritance dominant recessive etc of genetic diseases A sample pedigree is below These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute In a pedigree squares represent males and circles represent females Horizontal lines connecting a male and female represent mating Vertical lines extending downward from a couple represent their children Subsequent generations are therefore written underneath the parental generations and the oldest individuals are found at the top of the pedigree If the purpose of a pedigree is to analyze the pattern of inheritance of a particular trait it is customary to shade in the symbol of all individuals that possess this trait In the pedigree above the grandparents had two children a son and a daughter The son had the trait in question One of his four children also had the trait In the exercises below assume that the trait in question is a genetic disease or abnormality We will learn patterns of inheritance that have the following modes of inheritance autosomal dominant autosomal recessive X linked recessive


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UNC-Chapel Hill BIOL 101 - Pedigrees

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