BIOL 101 1st Edition Lecture 7 Outline of Last Lecture Membrane Structure and Function I Compare Contrast Passive Transport Simple Diffusion SD Passive Transport Facilitated Diffusion FD Active Transport AT II Passive Transport Osmosis III Bulk Transport what are the types Why the various types Which way will water move Outline of Current Lecture I Can Water Kill You a Case Studies II Energy and Enzymes a Functions of Enzymes Current Lecture Three True Stories Adapted from Water Can Kill from the National Center for Case Study Teaching in Science Case 1 Jennifer Strange Jennifer Strange was a 28 year old mother of three who entered a radio contest to try to win a Nintendo Wii game system for her children As part of KDND s Hold your wee for a Wii contest Jennifer drank bottle after bottle of water for hours without urinating Initially Jennifer seemed to be having fun joking lightheartedly with the radio hosts and obligingly downing an 8 ounce bottle of water every 15 minutes As the hours passed however she developed a splitting headache and dizziness Finally she couldn t take it anymore and ran to the bathroom and vomited Jennifer called her boss to say that she was going home for the day because her headache was excruciating and she was too sick for work Jennifer s mother found her that afternoon dead in her home Case 2 Cassandra Killpack After a 3 week trial a jury found Jennete Killpack 29 guilty of killing her 4 year old adopted These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute daughter Cassandra by forcing approximately a gallon of water down the girl s throat in an attempt to discipline her A few hours after the hydro discipline the Killpacks called the paramedics because Cassandra was unresponsive The paramedics delivered her to the hospital where she died later that day Medical investigation found that Cassandra s brain was swollen and the concentration of sodium in her blood and tissues was far below normal Case 3 James McBride James McBride a 25 year old police officer died after a 12 mile bike ride that was part of a training course Over the course of the ride James drank roughly three gallons of water that he brought with him in a pack During a session that focused on how to dismount a bike an instructor noticed that McBride looked ill and asked him to sit down McBride complained of dizziness and nausea and then vomited Officers initially thought he might have suffered heat stroke Unaware that James had already consumed so much water they gave him more water to cool him down while he sat out of the exercise When another officer hurt himself during the exercise an ambulance was summoned The paramedics noticed that James was convulsing and continuing to vomit so they brought him to the hospital He died in the hospital the next day 1 What sort of environment hypertonic isotonic hypotonic does consuming excessive amounts of pure water create in the body fluid that surrounds your cells What effect would this have on your cells 2 What types of symptoms did Jennifer Cassandra and James have in common Which organ or tissue seems to have been most affected 3 Keeping in mind your answers to questions 1 and 2 what do you think the immediate cause of death was for Jennifer Cassandra and James 4 Once you knew the cause of their symptoms what kind of emergency treatment might you try for a patient like Cassandra or James if you were the doctor in charge of their care Energy and Enzymes Class discussion What do enzymes do Brainstorm They lower the amount of activation energy they make cells more efficient they help processes move faster serve as a catalyst facilitate a reaction they break down polysaccharides they bind to a substrate they re made of proteins allow us to make metabolic pathways they are not used up work with cofactors coenzymes inorganic or small organic molecule Design an enzyme catalyzed condensation reaction that shows your understanding of the words ideas below The materials you have available as props are things we have available in a classroom such as classmates paper pens etc a active site b substrate c product d enzymes bring substrates together e some enzymes need co factors f enzymes are used over and over g enzymes can be inhibited at their active site or their allosteric site h enzyme activity is affected by environmental conditions
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