PSIO 121 5th Edition Lecture 10 Outline of Last Lecture Organization of Bone Outline of Current Lecture I Spongy Bone and Function II Compact Bone and Function III Bone Formation and Growth IV Intramembranous Ossification V Endochondral Ossification Current Lecture Rickets Disease Calcium deficient inorganic Scurvy Disease Collagen deficient organic Spongy Bone irregular lattice of thing plats called trabecullae osteocytes housed in lacunae Located in epiphysis of long bone surrounding marrow cavities flat short and irregular Contains osteocytes trabecullae osteoclasts lacuna osteoblasts concentric lamellae rings and caniculli Lamellae is made out of collagen fibers Function withstand forces from many directions trabecullae are aligned along lines of stress Lightens the skeleton Contains red marrow for hemopoiesis Compact Bone solid network of bone organized in concentric ring structure called osteons These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute Location external layer of all bones and diaphysis of long bones Function give long bones ability to withstand forces along longitudinal axis Osteon s are the functional unit of compact bone to carry nutrients and remove waste Compact bone contains osteocytes osteoclasts osteoblasts trabecullae lacuna lamellae concentric rings and caniculi ONLY FOUND IN Compact Bone osteons central canal perpherating canals interential lamellae circumferential lamellae Bone Formation and Growth Fontanel soft spot of infants where bone has not yet formed Epyphasis of large bone in infants is only made of cartilage Bones of the fetus are composed of 1 Loose connective tissue mesenchyme 2 Hyline cartilage Ossification development of bone by replacing Connective Tissue A Intramembraneous Ossification within membrane from mesenchyme to bone found in cranial bone mandible sternum clavicle Heterotropic bone formation Sesamoid bones Abnormal stress stimulate bone formation Steps 1 2 3 4 development of ossification center Calcification Formation of trabecullae Development of Periosteum B 1 2 3 4 5 6 Endochondral Ossification inside cartilage mesenchyme to cartilage to bone growth in length at epiphyseal plate development of cartilage model growth cartilage model development of primary ossification center development medullary cavity development 2nd ossification center formation of articular cartilage and epiphysis plate Primary vs Secondary Ossification
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