J210 Exam 3, Spring 2013 Page 1 of 11 J210 Microbiology & Immunology April 8, 2013 Examination 3 This examination consists of 70 questions. Questions 1 to 35 are worth 2 points each. Questions 36 to 70 are worth 1 point each which includes 5 bonus points on this exam. A perfect score equals 105 points. You have 90 minutes for this examination. All answer sheets are due at 9:40am, even if you arrived late. Make sure your last name, initials and university identification number are written on the Scantron sheet, and that the corresponding circles are filled in. You are encouraged to write on this question sheet and retain it after the exam. An answer key will be posted on Oncourse within 2 hours following the exam. Once the key has been posted, examination questions will be discussed on Oncourse only. You will be notified by email when scores are posted on Oncourse. Postscript: Questions 19 & 23 were withdrawn after this examJ210 Exam 3, Spring 2013 Page 2 of 11 Questions 1 to 35 (2 points each) MULTIPLE CHOICE: Select the one alternative that best completes the statement or answers the question. 1. Common virulence factor amongst bacteria that cause meningitis.A) IgA proteaseB) EndotoxinC) ExotoxinD) Fimbriae (pili)E) Capsule2. Which one of the following bacteria is least likely cause of food poisoning?A) Salmonella typhimuriumB) Shigella dysenteriaeC) Staphylococcus aureusD) Klebsiella pneumoniaeE) Escherichia coli3. Which one of the following bacteria is the most likely cause of epidemic meningitisA) Haemophilus influenzaB) Streptococcus pneumoniaeC) Streptococcus agalactiaeD) Neisseria meningitidisE) Staph aureus4. Alpha hemolytic Optochin-resistant streptococci that cause subacute endocarditisfollowing an invasive dental procedureA) Group AB) Group BC) Group DD) Group EE) Viridans group5. Gram (+), Catalase (-), β-hemolytic cocci which are Bacitracin-sensitive and causeimpetigo and erysipelas in young children and elderlyA) Staphylococcus aureusB) Staphylococcus epidermidisC) Streptococcus pyogenesD) Streptococcus agalactiaeE) Streptococcus faecalisJ210 Exam 3, Spring 2013 Page 3 of 11 6. A man presents at the clinic with a lesion on his wrist and several erythematous (red)areas along the length of his lower arm. He mentions that several weeks ago he picked arose in the garden for his wife and a thorn punctured his skin where the lesion formed.The agent which caused this is likelyA) Cladophialophora bantiana.B) Aspergillus flavus.C) Gyromitra esculenta.D) Malassezia furfur.E) Sporothrix schenkii.7. The principal reason for treating a case of acute strep sore throat with an antibacterial istoA) Make the patient more comfortableB) Enhance opsonizationC) Induce life-long immunityD) Prevent complicationsE) Reduce the appearance of resistance bacteria8. Today’s pertussis vaccineA) Is to be avoided, if possibleB) Is vastly improved and has little side effectsC) Has little need to be explained by healthcare workersD) Has little importance since the disease is so infrequentE) Causes hypersensitivity reactions9. Tetanus vaccinations should be boosted everyA) Time you may be exposedB) YearC) 5-10 yearsD) 25 yearsE) No boosters are necessary10. Which of the following produces a toxin that frequently kills American children viacontaminated meats (sometimes via restaurant chains) and may also cause HemolyticUremic Syndrome?A) Enterohemorrhagic E. coliB) Salmonella enteritidisC) Vibrio choleraD) Staph. aureusE) Shigella dysenteriaeJ210 Exam 3, Spring 2013 Page 4 of 11 11. Which of the following is most likely to cause peritonitis in a shooting victim?A) Enterococcus faecalisB) Strep. pneumoniaeC) Neisseria gonorrhoeaeD) Group A strepE) Chlamydia trachomatis12. Severe watery diarrhea with a "rotten-egg" smell accompanied by abdominal pain,bloating, and fever are signs and symptoms consistent withA) amebiasis.B) typhoid fever.C) pinworm.D) giardiasis.E) leishmaniasis.13. A 2 month old baby is brought in with a fever and vomiting. The baby cries when youmove its head. Spinal fluid is recovered and found to contain gram (-), pleomorphicrods and PMNs. The infectious agent is most likelyA) A virusB) Hemophilus influenzaeC) Strep. pneumoniaeD) Neisseria meningitidisE) E. coli14. A lesion seen in tertiary syphilis isA) A rashB) PetechiaeC) A chancreD) A gummaE) A pseudomembrane15. A common concern that dental work, such as dental cleaning, may cause isA) ErysipelasB) ImpetigoC) Toxic shock syndromeD) Subacute endocarditisE) Pelvic inflammatory disease16. Which of the following fungal infections was rare prior to the AIDS epidemic?A) mycetomasB) pulmonary cryptococcosisC) hypersensitivity aspergillosisD) Pneumocystis pneumoniaE) cutaneous candidiasisJ210 Exam 3, Spring 2013 Page 5 of 11 17. Which of the following organisms is identified by its ability to coagulate blood plasma?A) Legionella pneumophilaB) Enterococcus fecalisC) Staph. aureusD) Staph. epidermidisE) Group D strep.18. Streptococci are frequently classified byA) the bacteria's Lancefield antigen.B) the type of enzymes the bacteria produce.C) their staining properties.D) their ability to produce catalase.E) the diseases they produce.19. How do group A streptococci camouflage themselves from white blood cells?A) They stain as Gram-positive.B) They grow in chains or pairs.C) They produce streptokinase, which breaks down blood clots.D) They have hyaluronic acid capsules.E) They have protein M in their capsule, which destabilizes complement andinterferes with opsonization.20. Which of the following statements regarding Streptococcus pyogenes is FALSE?A) It produces protein A, which inhibits opsonization.B) It is beta-hemolytic.C) It has group A Lancefield antigens.D) It produces streptolysins.E) It is the causative agent of Scarlet Fever21. What is one feature that differentiates Staphylococcus aureus from other species ofstaphylococci?A) It produces exfoliative toxinsB) It has a slime layer capsuleC) It can produce coagulaseD) It can produce haluronydaseE) It can live on the surface of the skin and in cutaneous oil glands22. Otitis media may lead to dangerous meningitis in children due to infection withA) Streptococcus agalactiae.B) Streptococcus pneumoniae.C) Streptococcus mutans.D) Enterococcus.E) Mycoplasma pneumoniae.J210 Exam 3, Spring 2013 Page 6 of 11 23. Which of the following statements regarding Neisseria meningitidis is FALSE?A) There are vaccines available to prevent infection with all strains.B) A