KIN 3304 1nd Edition Lecture 19 Outline of Last Lecture I Lymphatic System II Functions of Lymphoid System III Thymus IV Other Stuf V Functions of Lymphatic System VI Lymphedema VII Functions of Lymphatic System cont VIII Lymphatic Capillaries IX Lymphatic Collecting Vessels X Deep Lymphatics XI Figure 23 16 XII Lymphomas XIII Figure 23 4 XIV Thoracic Duct XV Lymphocytes XVI Diferent Types of Lymphocytes Outline of Current Lecture I T Cells a few of them These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute II B Cells III NK Cells IV B Cells cont V Fist Clinical Trials on Vaccination VI Louis Pasteur Current Lecture I T Cells a few of them a 80 of circulating lymphocytes i CTLs antiviral 1 CMI cell mediated immunity ii TH Cells 1 TH9 TH17 cells 2 CD4 T helper cells CD8r CTLs iii Tregs suppressor T cells iv Memory T Cells 1 Activated T cells following Ag exposure 2 Activated again when encountering same Ag b T Cells help combat stuf II III IV V B Cells a 10 15 of circulating lymphocytes b Plasmocytes antibodies incredibly specific humorous 10 10 12 c Some antibodies are very specific NK Cells a NK Cells 5 10 b Immunological surveillance c Self vs non self d Attacks things it doesn t recognize and kills it B cells cont a Antibody production b Memory Cell c Comes from bursa of fabricus d the chart after the second time being infected people will have more antibodies attack First Clinical Trials on Vaccination a Chinese and Turks 15th century i Dried pustules inhaled in settled in cuts in skin ii Popped blisters of infected people and put it in their skin iii first vaccinations VI b 1718 Lady Mantagu used this on own children c 1798 Edward Jennet and Blossom and some serous IRB issues i Milker people rarely got small pox if exposed to cow pox you ll be resilient to small pox ii First trial based of of scientific evidence Louis Pasteur a Injected chicken with an old culture of bacterium that caused fowl cholera b Chickens became ill but didn t die c Due to funding issues used previously injected chickens to inject a new batch of the virus d Chickens were completely protected from disease e Pasteur hypothesized aging weakness virulence called attenuated strain vacca or cow vaccine
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