7.013 Lecture 12.7.07Introduction1.How the course works2.What you will learn1.How the course worksmit.edu/7.01x/7.013Profs. Hazel Sive David Gifford Richard YoungInstructor Dr. Phil LessardTeaching Assistants Jes AlexanderAnu BhimavarapuMegan ColeDerek ChuEllie GrahamShilpa JoshiVarsha KeelaraJim MediatoreShannon NeesLeah OkamuraTania SierraJessica YuTutorsAshlie BrownSophia KamranJanet LiStephanie WangKathy XieSylvia YangLecturesMWF 11-12 10-250Be thereNo audio, no notes posted Powerpoints posted after lectureRecitationTo change recitation section [email protected] start Wed. Feb 7There are two sections per weekProblem setsPosted on web siteDue by 5pm on due datePut in your TA slot on cart outside 68-120LATE PROBLEM SETS = ZEROGradesExams (in class) 3 x 100 = 300Final 200Problem sets 6 x 20 = 120All exams count, no make up examsLowest problem set droppedPROBLEM SETS Must be your own workNo regradesEXAM REGRADESAll exams are photocopied and regraded from the copyText BookLife, Science of Biology 7ed by Purves et alOther material on website72. What you will learn(and why you are here)STARTSTARTFOUNDATIONSFOUNDATIONSHow-to 1How-to 1FORMATIONFORMATIONHow-to 2How-to 2SYSTEMSSYSTEMSPROBLEMSPROBLEMSBIOCHEM GENETICS CELL BIO.MOL. BIOSTEM CELLS,CLONINGREC. DNACELL TYPE 3DSTRUCTUREVIRUSESCANCERHUMANDISEASELIFELIFENERVOUSIMMUNESYSTEMSBIOLOGYFUTUREFUTURESTARTSTARTFOUNDATIONSFOUNDATIONSHow-to 1How-to 1FORMATIONFORMATIONHow-to 2How-to 2SYSTEMSSYSTEMSPROBLEMSPROBLEMSBIOCHEM GENETICS CELL BIO.MOL. BIOSTEM CELLS,CLONINGREC. DNACELL TYPE 3DSTRUCTUREVIRUSESCANCERHUMANDISEASELIFELIFENERVOUSIMMUNEGENOMICSSYSTEMSBIOLOGYFUTUREFUTUREModel organisms1Frog cell division: 0 - 10 hours after fertilization/sPink Floyd/ another brick in the wall3Hayashi and Carthew, 2004Soap bubble organization and cell shape in the fly retina43D structureof the humanheart5Cell connections and circuitsin the nervous system67TGTTGGGATTCCATTGTTGATAAAGGCTATAATATTAGGTATACAGAATATACTAGAAGTTCTCCTCGAGGATT TAGGAATCCATAAAAGGGAATCTGCAATTCTACACAATTCTATAAATATTATTATCATCGTTTTATATGTTAATATTCATTGATCCTATTACATTATCAATCCTTGCGTTTCAGCTTCCACTAATTTAGATGACTATTTCTCATCATTTGCGTCATCTTCTAACA CCGTATATGAT AATATACTAGTAACGTAAATACTAGTTAGTAGATGATAGTTGA TTTTTATTCCAACATACCACCCATAATGTAATAGATCTAATGAATCCATTTGTTTGTTAATAGTTTAAATGTTTTTATCGGAAGAGGTTTTGTCATCACATCAGCAATGTTCTTCTTGGTCTCGATGTAGTA TACGTATAAATTATTACCTGATACTTCATCTCT AAGTCTCATTGCCTTTGTGCCAAAAAATCTGTTTCTAAATTTCTCTTCATTTGTAGACTTAATTATACTGATCGTTGATCTACTATCAGTAAGTGAGCCTTTAATAATTGGTTTCTTGTTAAGTTCTTGCACAAGGTGACTGAGGTTATTCAATAGCGGAATAGCTTCACTGACTGCGTGTATTTCTGCTTCTGTAGTTGAAGTGCAT GTTAACGAAGCCTTTGTCGACTTTCCTCCAATCACTTTTCCGTTGAGTAGGAAAATGTTACCAATTTGTGACTTGTAATATGGTTGGTTACCATATG AAGCATCGCTTATTGCGACTAGTTTATTATCTGGCTTGGTAGGTTTGTTTTTGTGCCATATTAATTGTTTATCTCTAGTGTCCCACATGAATTGTATTAACTCATATGTCA TGTCTAAAACTTGCCTAGAGGGGAATAGTATATGTTGAGCAAGTGTGTTGATGTAGTATAGTAAGTCAAATCTAAATTTATATCCAACATATGAAGCTAGACCAATC AACTTTTGCATTTCATGCACTTTCTCTTTGTATTCATCTTCATCTATTTCTAGTTCATCCTGGTCTA TATAATGACCTGGTTGACCTGGAGCTCTAAGTTTCTTTCCTTTTGGGTTCAAAGGTACGTTTAGTTTGGGTAATTTTTCTGTCAAGGA TTTTTCCATACCTAATTTCATGTACTTGCTTCTTTGATATTTGATCTCTAATCCAAG TATGTCGTACTGAATTTCGTTA TCACCTTCACC CAGATTTATTA TCTTTGTATCGTATTGTTTCTTGAGTGTTGTTATGATTTTCTTAT TTGCATTTAAG TCTTTGCTGAACAATATCATATCATCAACGAATAAGCAAATTGTTACTTGACTATTCTTAAATACGCATGACCATCCACGAACTTCTTCCATACCACACTGTTTTATCAGGTATGATTT GATAGTTTCGT ACCAGTTCGCT CCACTTTGTTTCAATCCATAAAGTGATTTCTTCA AACGTATCAACTTATCATTCATTCCTAAATGTGGTGGAGGTCTTATGTATAATT CTTCTTTGATGTCTGCATACAA ATATGCCGAAGATATGTCTAATTGTGTAATATAGTAGTTATTGTCTAATGCAAGT GACAGGGATGTCATTAATGCA TAGTGATGTACGGTATTGGATTGCATGCCTGAGTCGTAAGTGTCAGGATGCTGAATATCACCTCTTGCAACAAATCTAGCTTTATGAGTACCGTCACGTTTCCTGTTGAAGATAAACATTGAATTTATTACTCTTTTAGGGTCTATTTCTTTTCTGTCATAATA TTTGTCAGTGTCCCAAGTATTC ATTTTCAATAG TTGGTTGACTTCTTTGTGGTATGCTTCGATATATTTTTCCTTTTCTTTAATATCTTTATTATAGGTGA TTGCCTCATCGTATCTTAAGGT TGTCCGTATTGGTTTGATTGATTTTACTGCTTTTACAGCTGCAATCAGGTGAATTCGTTTCTTCGATCTCGGAGGTTCTAAACTACGCATATTCTTAGTATTCCATGTGTCTCGTGATACCTTAATTTCAGTTTCATTATCTTCTAATGATCTTTTCTTACTGTTGATAGTAGTATAGGCATTAGA GTCACCAATACCACCCAAACTGGAATTAGTTTGATGAGAATTTATCGGTGGGAGTTCTTTAAATGGGTCAGGGAATTCGGTAGGAGATTCTGGAGGTAGATCAGGGAGTGGGAGATCAGCGATGATAGATTCCTCGGTATTCTGTTCAGAAA CAGTAGTTGGCGTTTTGATAGGAACAATATTG TGCGATGAATTATTTTCCGGTGGAGAAGCATCGATTGAAGGTGAACGGTGTATAATCCTTTTCT CAGTCTCTTGG TCACTTATCTGCGGAACAGTTTTGTTGTTGGTAC CACCCGTACTGGATATTGGTACGTTTGTATGATTAGTCTCATTTTCACTGTACGAGTCTGAGTGT CTGAAATCTTTAGATTTACTGGCGTGCGACGA CTCATGTGTGTTAGATTGGGACATGGGAGCAAGTAAAGGAACA TTTAATTTATGCATACCACCCGAACCGGTACTCTCGATATTGGAAATTTGGGGGGTGCTAGATC TCTTCTTTGATGGAAGAATATTAGATTCAGATATGTTGGGGTCAA CTTCTCTGGGTGCGCGAATATTGGTTTTAGAAACACGTTTCGA ATCTTCAGTATGAGTTGACGGAGGTGTGGAATCGGTTGGACTCACAGCTTTTGAAAGGACATTTCTCGGTTGCTCAGGATGTAGTTCAATGTCGGATTGGAAGTCATGGTCAGATTCTATGTTAAGATCATTGGATTCTTGGATCTCATTTGACGCAATGAACGAATGATATGAAGCAGTTAAACGGTTTAAG TCTTCATCGAA AGTGAGTGCGTCGTAATTGAATTGATCTAATCTGGATTCCTTGCCCTGAAGAATAACATAGTTAGTTGTATCTACTGTCTTCTTTAAGGATGGAAGATAGATGATATATCCATAAGAGTTTCGAGACGGA TGTAGAGCGTAGCCTGGGATGCCACGAGGATGTATTTTGGAGTTAGGGTTGTGAT CATTGACGATAACAGGTTGACCGAAAGGTAACAAAGTACTGATATCAAGTCCTGCCAAGCCAGCATGTTGTCTTGCAGATTTTTTGCTTTTAGGTGAAGCTAGTGAATTTCTCACAATAGTAGAAAATT CGATTGCAGAGAACCATAAAT GGTTCGGTAAACCACTACATTGCAGTTGAGTACGGCAGTCATCTAATAAGGTACGGTTTAGCCGTTCAGCGACTCC ATGTGCTCGGGAATCCGCTGTGGTTGTATAGC ATGGAGTTATACCATTTTTTTCAAGGAATTTATGGAGAGTTCTGTTAGTATACTCAGAACCACGGTCCATTTGTATAACCAAGACACTGGCCTGAAACTGGTTTTTAATAAAAGCTAGTATCGTAGTAAAAACATCGAGGATAGAGTCCTCGCGACGGTCGTGTAATGGATAAACCCAACG GAATTTTGTTGTCTCATCAGTA AATGAGATGAAATAGGATGGTGC ACTATTTGGTA GGTTGTGAACTGGACCAAATA TGTCAGTATGT AGGTATTGAAAGGGTTCGTATGAATTTTGGTATTTTAGTCGTG AACCTTTGATATGTCTGTGTTTGGTGCTTTTGCCGATTAAACAAT CAGGACATTGATAGTCAATAG CACTAGACCAGTCGACATCTGATTCGTTAAAATACGTGATGGTGTTATTTTTAAGTGAGTATCGAATTGTCTGTGCATTGGCATGCGCAAGCATTCGATGAATGAAAGGATAAGGATATTTGCGTGTACTTTCACTTGTATGGACATTATTGATGGTGGGTACGGAGATATTTGATGGAAGCAAGTACTTTTTAGATACCCAGTAAAAGTCTCCATATTTTACGATAGGTGCAAGTACAGTGCCGTCAGATCGTTCTAA GACGTTTTTGG TAAAGCATGCTGTGATATCTACTGCAGCCAAT TCATTCAAACT GAGTAAGTCATAGGCTATGTTAGGAGTGTGCAATACCTTTATTGATGTTTTGGTGTTGTCCTGGAAGTGAAATTGTAGGTCACCAATAGCGTTAATTG GTATATTTCTTTTTTGAGCATCAACTACGTTTA TGCCAGGATTAGATGATGCTGAGTGTATGTGGTGAGCAGATCTTATAAGGGTTCGTGATGCTCCTGAATCGAGAAGGAGGTGTCCAGGGAGTTCATCATCAGAATGATTAGTGTGATTTACCGTAGATTCAGTAAGTTCCTGGCCTAAGATGAAGGTCGT GCTTATTGTTCAATTGAATCGGTTCAGTAGTTGATTTACTGATGGAATCGTTGTCCGTGCTGGGAGAGTTATTAGATGTGGATACATTGTGAGCCCTGGCTGTTTTCGATTTCGAATTATTTGTTTTTTGAG GATTCCGAGCTATAACTTTGGGT
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