So far:1. What is a cell?2. What do cells do?Replicating, membrane-bound entity, with metabolic functions.Maintenance metabolism, specific function, division, death, move, change shape…..7.0133.23.07Cell Biology III“cellular decisions”1. Cell division cycle1Frog cell division: 0 - 10 hours after fertilization/s2See slide #3, lecture 1. This is the same movie!!Budding yeast:used to isolate cell cycle mutantsLee Hartwell, Paul Nurse, Tim Hunt: Nobel Prize 20013Sea urchin452. Cell death (apoptosis)6Metamorphosis in frogsProf. Robert HorvitzMIT Biology DeptNobel Prize 2002Apoptosis (“programmed cell death”)7Caenorhabditis elegansSoil nematode~1,000 cells~130 undergo apoptosisEach nucleus is stained blue89Apoptosis in lymphocytes10DNA fragments in apoptotic cells1112Have a great Spring
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