BS 161 1st Edition Lecture 33 Outline of Last Lecture I Transcription translation Outline of Current Lecture II Control gene expression Current Lecture prokaryotes and eukaryotes alter gene expression in response to their changing environment in multicellular eukaryotes gene expression regulates development and is responsible for differences in cell types RNA molecules play many roles in regulating gene expression in eukaryotes gene regulation can be transcriptional post transcriptional translational post translational transcriptional control slow but efficient translational control allows a cell to change quickly when proteins are produced post translational control provides the most rapid response a cell can regulate the production of enzymes by feedback inhibition or by gene regulation gene expression in bacteria is controlled by the operon model operon the DNA that includes the operator the promoter and the genes called cistrons they control repressor protein that can switch off the operon prevents gene transcription by binding to the operator and blocking RNA polymerase corepressor a molecule that cooperates with a repressor protein to switch an operon off anabolic pathway repressible regulation default on catabolic pathway inducible regulaton default off
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