Essential Elements of Biochemistry BCHM 3050 Dr Srikripa Chandrasekaran Lecture 4 20 15 Respiratory Electron Transport continued I External Glycolytic NADH is Not Directly Accessible to Respiratory Electron Transport A 1 pyruvate 1 1 NADH 3 NADH 1 FADH2 1 ATP 2 If it goes through the Kreb s cycle there is 1 ATP accumulated during Substrate Level Phosphorylation In the liver the Malate Aspartate shuttle is present B C 10 protons for every NADH in the liver because the Malate Aspartate shuttle has the NADH enter Complex 1 D 6 protons for every NADH in a muscle or brain because the NADH E enters Complex 2 In the liver 10 NADH 100 protons goes to Complex 1 and 2 FADH2 12 protons goes to Complex 2 112 protons total F 28 ATP 4 ATP 32 ATP total in the liver G 104 protons in the muscle or the brain 26 ATP 4 ATP 30 ATP total H 32 ATP in the liver 30 ATP in the muscle or the brain I In reality the amount of ATP that is actually obtain is 25 29 ATP because energy is lost as heat and other ways throughout the process external factors like pH and the level of activity can influence the number of ATP obtained 1
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