BMB 401 Self Assessment Lecture 31a: Proteases that Hydrolyze Dietary Proteins 1) Protein digestion begins in the ________Stomach_______________________2) The zymogen released in this organ becomes activated to produce a protease that specifically acts in this environment. a) This zymogen is__________________ Pepsinogen___________________________b) The activated protease is_________________ Pepsin __________________c) This zymogen is activated by _____________ Low pH _________________2) Where is the protease enteropeptidase found?______________________________________________ on the luminal surface of enterocytes (Note: enterocytes are epithelial cells that line the luminal surface of the small intestine).____ 3) Enteropeptidase activates a specific zymogen that initiates a protease cascade.a) What is this zymogen? ___________Trypsinogen________________b) Where is this zymogen produced? _____________Pancreas______________________________c) What is the name of the activated protease formed from this zymogen? _____________Trypsin________________________________________4) Please name two zymogens activated by the protease in 3c and their activated counterparts.a) Zymogen_________Chymotrypsinogen_______________________________________________b) Protease____________Chymotrypsin _________________________________________c) Zymogen___________Proelastase _______________________________________________d) Protease_____________Elastase ____________________________________________________e) Zymogen___________Procarboxypeptidase ______________________________f) Protease_____________ Carboxypeptidase
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