BMB401 Exam I Practice Exam ID Page LOGARITHMS THAT MIGHT BE USEFUL ANTILOGS THAT MAY BE USEFULUS13Amino Acid 1- and 3-letter CodesA Ala Alanine M Met MethionineC Cys Cysteine N Asn AsparagineD Asp Aspartate P Pro ProlineE Glu Glutamate Q Gln GlutamineF Phe Phenylalanine R Arg ArginineG Gly Glycine S Ser SerineH His Histidine T Thr ThreonineI Ile Isoleucine V Val ValineK Lys Lysine W Trp TryptophanL Leu Leucine Y Tyr TyrosineUnit Conversion nM = 10-9 molar, µM=10-6 molar, mM= 10-3 molarpKas of Amino Acid Functional Groups1log 0.01 = -2log 0.1 = -1log 1 = 0log 2 = 0.30log 3 = 0.48log 4 = 0.60log 5 = 0.70log 6 = 0.78anti log 1 = 10anti log 2 = 100anti log 3 = 1000anti log -1 = 1/10anti log -2 = 1/100anti log -3 = 1/ 1000log 7 = 0.84log 8 = 0.90log 9 = 0.95log 10 = 1.0log 100 = 2.0BMB401 Exam I Practice Exam ID Page 1) Please choose the true statement:a. The four most prevalent elements in living things are hydrogen, carbon, oxygen, and phosphorus. b. The major attractive force that is formed between two methyl groups is fixed-dipole, dipole.c. The attractive bond energy between two ions is directly proportional to the magnitude of the charge on the ions. d. Hydrophobic interactions arise because of charge repulsion between the solution and the hydrophobic solute. 2) Please choose the true statement:a. Our bodies represent closed systems. b. The buffering capacity of a buffering system is greatest at the pKa of the conjugate acid. c. Each buffer has one optimal buffering range. d. The prominent buffering system of the cell is the carbonic acid, bicarbonate buffering system.3) The First Law of Thermodynamics says that the energy of any system is constant. True False4) Please choose the true statement:a. The entropy of the universe always decreases.b. ∆ S of the universe must always be a negative number.c. ∆G˚’ represents the free energy of a system in aqueous solution at pH 7 and at standard temperature and pressure. d. All the above are true5) Please choose the true statement:a. Glycine is in the L-configuration, but proline is not, because it is an imide.b. Aspartate is a basic amino acid because its guanidinium group can pick up a proton at physiologic pH to become protonated.c. Of the 20 amino acids found in proteins, those classified as basic, have a full formal positive charge at physiologic pH.d. All the above are true.e. Only a and c are true. 6) Please choose the correct groupings: where P=protein, C= carbohydrates, N = nucleic acids and L = Lipids. a. Form covalently linked polymeric structures: P, C, N, Lb. Found in the cell membrane, either as primary constituents of the membrane itself or as surface structures: P, C, Lc. Provide energy either through catabolism or through hydrolysis of high energy bonds: P, C, N, Ld. All the above are truee. Only b and c are true7) The pI of a protein is the pH at which the protein has no charge, as all amino acid side chains and both the terminal alpha-carboxy and -amino groups are neutral in charge. True False8) The nitrogenous bases in DNA are Cytosine Guanine Thymine and Uracil. True False9) Please choose the true statement such that an ionic salt bridge can be formed between the side chains of the amino acids listed at the stated pH a. Arginine and Histidine, at pH 10b. Histidine and Aspartate, at pH 3c. Glutamine and Histidine, at pH 8d. Proline and Lysine at pH 7e. None of the above can form a salt bridge at these described pH values.US132BMB401 Exam I Practice Exam ID Page 10) Two ions in an ionic bond in H2O have a bond energy of - 5.9 kJmol-1. Which of the following is true: a. In hexane, at the same distance, this bond energy would have a greater value than 5.9 and be positive.b. In hexane, at the same distance, this bond energy would have a greater value than 5.9 and be negative.c. If these two ions were left in solution but somehow moved further apart, the bond energy between them would become more negative. (a higher value than 5.9 and still negative) d. If the one of these ions were switched to have an opposite charge of the same magnitude, and both ions remained in water and at the same distance, the bond energy would be +5.9 kJmol-1.e. Only a, c and d are truef. Only b and d are true. 11) Please choose the true statement:a. The pI of a protein is the pH at which the protein as a whole is neutral in charge.b. The pI is the pH at which all of the amino acids comprising that protein are neutrally charged c. The pI of a protein is the pH at which all of its amino acid R-groups are deprotonated.d. There are no true answers here.12) Select the correct statement to finish this sentence correctly : In describing the genetic code:a. codons in the transcript are overlapping sets of 3 bases corresponding to 1 amino acid.b. one codon can correspond to more than one amino acid.c. one amino acid can be coded by two or more codons.d. each of the 64 possible combinations of three bases corresponds to a particular amino acid.e. Both b and d are true.f. Both c and d are true.13) Which of the following is NOT one of the weak, non-covalent forces frequently involved in biomolecular interactions?a. Disulfide bondsb. Hydrophobic interactionsc. Ionic interactionsd. Hydrogen bonds14) Sickle cell anemia, Hs, confers a survival advantage in persons:a. Homozygous for Hs , b. b) Heterozygous for Hs , c. Either Homozygous or Heterozygous for Hs , d. This allele does not confer any advantage.15) Which of the following is FALSE?a. In aqueous solution, proteins are surrounded by a hydration shell of water molecules b. In aqueous solution, proteins form hydrogen bonds with water molecules.c. In aqueous solution, polar amino acids are most commonly on the outside of a protein, and interact with the solution.d. In a lipid environment, and in an aqueous environment, the amino acids with hydrophobic side chains are most commonly buried on the inside of the protein rather than the outside. 16) Please choose the true statement:a. The normal 3-dimensional structure of a protein is called its primary structure.b. A denatured protein is one that has become proteolyzed. c. Denatured proteins generally do not show loss of normal function.d. Denaturing agents can often disrupt the weak non-covalent interactions in a
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