1st Edition
BIO 344: Molecular Biology
School: University of Texas at Austin (UT )
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Pages: 5Discussion of genome structure in regards to mobile elements-- transposons and piRNA
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Pages: 5Discussion of mechanism for protein degradation with ubiquitin and p53
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Pages: 3Video on prions-- the causes of prion diseases and possible methods of transmission
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Pages: 5Discussion of RNAi-- antisense and sense dsRNA and mechanism for RNAi with silencing RNA, dicer, RISC, and argonaut
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Pages: 5Discussion of translation in bacteria and eukaryotes-- how the ribosome begins and elongates translation and how the 5' cap and poly a tail affect translation
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Pages: 5Discussion of the genetic code-- breaking the code-- how it is read and translated with the help of tRNAs, the ribosome, and amino acyl tRNA synthetase
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Pages: 4Discussion of RNA editing-- example in glutamate receptors: ADAR in relation to GluR-B. Also discussed RNA directing other RNA modifications cotranscriptionally with snoRNA.
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Pages: 5Discussion of RNA processing methods-- alternative splicing, capping, poly adenylation and their effects on export and translation.
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Pages: 3Alternative splicing-- observed in sex determination of drosophilia, activators and repressor effects on mRNA
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Pages: 5Discussion of splicing, components of introns, exons, spliceosomes and effects of mutations in introns or exons
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Pages: 6Chromatin remodeling- methylation and acetylation, histone code, stress induced epigenetic control
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Pages: 5Description of integrating glucose and lactose signals and general transcription in bacteria. Discuss how gene expression is altered.
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Pages: 4Structure and function of the lac repressor and its operator, the effects of mutations on the repressor, and specificity and affinity
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Pages: 3Meselson Stahl paper-- interpretation of data and results. How to read a paper
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Pages: 5Discussion of DNA polymerization and chemotherapeutics. Also discussed technology such as radioactive labeling, fluorescent labeling, Sanger sequencing, PCR, and NextGen
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Pages: 4Discussion of genome structure and differences between bacteria and human genomes. Also discussed DNA structure