BS 161 1st Edition Lecture 25 Outline of Last Lecture I Cell cycle I Outline of Current Lecture II Cell cycle I continued Current Lecture prophase prometaphase nuclear envelope breaks down metaphase mitotic spindles must form correctly and connect to chromosomes aligned equidistant from the two poles via kinetochore proteins at the centromere anaphase chromatids must separate correctly and move to the poles telophase nuclear envelope and nucleolus reforms microtubules MTs tubulin polymers centrosome MT organizing center kinetochores centromeric protein complexes that function in attaching spindle MTs to the chromatid spindle comprised of centrosome spindle MTs and asters MTs change location and abundance in mitotic cell cycle Important points about cell cycle The prokaryotic cell division process is not a good model for eukaryotic cell division The four phase cell cycle is similar in all eukaryotic cells Chromosome nuclear and centrosome events must be coordinated in mitosis The checkpoint in Gap 1 determines whether a cell will synthesize DNA cytokinesis usually follows mitosis in animal cells cleavage furrow of actin and myosin forms a ring around the equatorial region of the dividing cell attached to the plasma membrane in plant cells cell plate of cell wall material is built midway between two nuclei by Golgi derived vesicles collecting on the spindle
View Full Document
Unlocking...