Chapter 17 MULTIPLE CHOICE Choose the one alternative that best completes the statement or answers the question 1 The antibodies found on the surface of B cells and which always exist as monomers are A IgG B IgM C IgA D IgD E IgE Answer D 2 A Treg cell deficiency could result in A increased number of bacterial infections B increased severity of bacterial infections C transplant rejection D increased number of viral infections E autoimmunity Answer E 3 Large antibodies that agglutinate antigens are A IgG B IgM C IgA D IgD E IgE D c and d E b and d Answer B 4 What type of immunity results from recovery from mumps A innate immunity B naturally acquired active immunity C naturally acquired passive immunity D artificially acquired active immunity E artificially acquired passive immunity Answer B Figure 17 2 5 In Figure 17 2 which areas represent antigen binding sites A a and b B a and c C b and c Answer A 1 6 Which of the following is the best definition of epitope A specific regions on antigens that interact with T cell receptors B specific regions on antigens that interact with haptens C specific regions on antigens that interact with antibodies D specific regions on antigens that interact with MHC class molecules E specific regions on antigens that interact with perforins Answer C Figure 17 1 7 In Figure 17 1 which letter on the graph indicates the highest antibody titer during the patient s response to a second antigen A a B b C c D d E e Answer E 8 ADCC is a process that is most effective in destroying A extracellular viruses B bacterial toxins C bacterial pathogens D eukaryotic pathogens E virus infected host cells Answer D 9 Thymic selection A destroys MHC molecules B destroys B cells that make antibodies against self C destroys CD4 cells that attack self D destroys T cells that do not recognize self molecules of MHC E activates B cells Answer D 10 Which of the following is NOT a characteristic of cellular immunity A B cells make antibodies B It can inhibit the immune response C Cells are processed in the thymus gland D T cells react with antigens E The cells originate in bone marrow Answer A 2 11 The specificity of an antibody is due to A its valence B the H chains C the L chains D the constant portions of the H and L chains E the variable portions of the H and L chains Answer E Figure 17 1 12 In Figure 17 1 which letter on the graph indicates the patient s secondary response to an antigen A a B b C c D d E e Answer C 13 The antibodies found in mucus saliva and tears are A IgG B IgM C IgA D IgD E IgE D IgD E IgE Answer C 14 The antibodies that can bind to large parasites are A IgG B IgM C IgA Answer E 15 Newborns immunity due to the transfer of antibodies across the placenta is an example of A innate immunity B naturally acquired active immunity C naturally acquired passive immunity D artificially acquired active immunity E artificially acquired passive immunity Answer C 16 The presence of which of the following indicates a current infection rather than a previous infection or vaccination A IgD B IgG C IgA D IgM E IgE Answer D 3 17 Which of the following is the best definition of antigen A something foreign in the body B a chemical that elicits an antibody response and can combine with these antibodies C a pathogen D a protein that combines with antibodies E a chemical that combines with antibodies Answer B 18 Cytokines released by TH1 cells A convert TH1 cells to TH2 cells B convert TH2 cells to TH1 cells C convert B cells to T cells D kill parasites E activate CD8 cells to CTLs Answer E 19 Which of the following is NOT a characteristic of B cells A They have antibodies on their surfaces B They are responsible for the memory response C They recognize antigens associated with MHC I D They originate in bone marrow E They are responsible for antibody formation Answer C 20 Which of the following destroys virus infected cells A CTL B B cells C Treg D TH E dendritic cells Answer A 21 IL 2 produced by TH cells A stimulates TH cell maturation B activates macrophages C activates TC cells to CTLs D causes phagocytosis E activates antigen presenting cells Answer A 4 Figure 17 2 22 In Figure 17 2 which areas are similar for all IgG antibodies A a and b B a and c C b and c D c and d Answer D 23 CD4 T cells are activated by A cytokines released by dendritic cells B interaction between TCRs and MHC II C complement D interaction between CD4 and MHC II E cytokines released by B cells Answer D 24 Which of the following cells is NOT an APC A natural killer cells B macrophages C immature B cells D dentritic cells E None of the answers is correct all of these are APCs Answer A 25 Which of the following recognizes antigens displayed on host cells with MHC II A TC cell B B cell C basophil D natural killer cell E TH cell Answer E 5 E b and d Figure 17 1 26 In Figure 17 1 the arrow at time c indicates A exposure to a new antigen B the time of exposure to the same antigen as at time a C the secondary response D the T cell response E the primary response Answer C 27 Which of the following statements about natural killer cells is FALSE A They destroy tumor cells B They destroy cells lacking MHC I C They are stimulated by an antigen D They destroy virus infected cells E None of the answers are correct all of these statements are true Answer C 28 Which of the following statements about IL 12 is FALSE A It causes TH cells to respond to HIV B It causes autoimmune diseases C It inhibits some tumor cells D It activates the TH1 pathway E It activates macrophages Answer B 29 What type of immunity results from transfer of antibodies from one individual to a susceptible individual by means of injection A innate immunity B naturally acquired active immunity C naturally acquired passive immunity D artificially acquired active immunity E artificially acquired passive immunity Answer E 6 30 Plasma cells are activated by a n A antigen B memory cell C B cell D T cell E APC Answer A 31 Which of the following WBCs are NOT lymphocytes A helper T cells B cytotoxic T cells C B cells D M cells E NK cells Answer D 32 What type of immunity results from vaccination A innate immunity B naturally acquired active immunity C naturally acquired passive immunity D artificially acquired active immunity E artificially acquired passive immunity Answer D 33 The following events elicit an …