MCB 450 1st Edition Lecture 21Outline of Last Lecture I. Fatty acid catabolism:a. β-oxidation of saturated (even C) fatty acids and the ATP count b. β-oxidation of saturated (uneven C) fatty acidsc. β-oxidation of polyunsaturated fatty acidsd. Ketone bodiesII. Fatty acid biosynthesisa. Overviewb. How the cell ensures supply of the precursors acetyl-CoA and NADPHc. Steps of biosynthesisd. Overall equation for the synthesis of one molecule of palmitic acid (16:0)e. Regulation of fatty acid metabolism (allosteric, covalent, hormonalf.Outline of Current Lecture I. Central Dogma reviewII. Differences between DNA and RNAIII. Nitrogenous basesIV. NucleotidesV. Nucleic acids (DNA) a. Composition of DNA (Chargaff’s Rule)b. The DNA double helix (Watson-Crick)c. Secondary structure of DNA (A, B, Z DNA)d. Denaturation and Renaturation of DNAe. Higher order packing of DNA in cells (chromosomes and histones)VI. Nucleic acids (RNA) secondary and tertiary structures of RNACurrent LectureCentral Dogma-DNA is replicated then undergoes transcription to become RNA-RNA is translated to proteinsDNA and RNA differ in the sugar component and one of the bases-Deoxyribose has a H atom present at the 2'-carbon atom opposed to an OH which is present in ribose-DNA contains thymine where RNA contains uracilConventions in writing DNA/RNA sequencesThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.-DNAoA is paired with ToG is paired with C-RNA oA is paired with UDouble Helix-Allows for the accurate transmission of
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