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UIUC MCB 450 - Nucleotides and Nucleic Acids

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MCB 450 1st Edition Lecture 21 Outline of Last Lecture I Fatty acid catabolism a oxidation of saturated even C fatty acids and the ATP count b oxidation of saturated uneven C fatty acids c oxidation of polyunsaturated fatty acids d Ketone bodies II Fatty acid biosynthesis a Overview b How the cell ensures supply of the precursors acetyl CoA and NADPH c Steps of biosynthesis d Overall equation for the synthesis of one molecule of palmitic acid 16 0 e Regulation of fatty acid metabolism allosteric covalent hormonal f Outline of Current Lecture I Central Dogma review II Differences between DNA and RNA III Nitrogenous bases IV Nucleotides V Nucleic acids DNA a Composition of DNA Chargaff s Rule b The DNA double helix Watson Crick c Secondary structure of DNA A B Z DNA d Denaturation and Renaturation of DNA e Higher order packing of DNA in cells chromosomes and histones VI Nucleic acids RNA secondary and tertiary structures of RNA Current Lecture Central Dogma DNA is replicated then undergoes transcription to become RNA RNA is translated to proteins DNA and RNA differ in the sugar component and one of the bases Deoxyribose has a H atom present at the 2 carbon atom opposed to an OH which is present in ribose DNA contains thymine where RNA contains uracil Conventions in writing DNA RNA sequences These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute DNA o A is paired with T o G is paired with C RNA o A is paired with U Double Helix Allows for the accurate transmission of information


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