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Muscle Physiology & Muscle Fiber Anatomy1. Electrochemical equilibrium = _________ __________.2. If resting potential can change it means that the cells are ______________.3. Name 2 types of cells that are excitable.4. Muscle and nerve cells have __________ channels, which make them excitable.5. Type of gated Active Channel where chemical binds to a receptor to open gate?6. Type of gated Active Channel where have change in electrical charge within cell?7. Chemical changes in the cell make it go from resting potential to an ________ ___________.8. ____________ __________ is made up of the synaptic knob & motor plate.9. ______________ is the region with many channels that are chemically regulated.10. _________________ are bags of neurotransmitters that can break and release chemicals.11. Events by which transmission of an action potential along sarcolemma causes myofilaments to slide?12. ______________ is the cell membrane of skeletal cell.13. _______________ are the indentation along the sarcolemma.14. __________________ are “bags” around the T-tubules.15. __________ = T-tubule + 2 terminal cristerna16. What chemical bursts the synaptic vesicles? 17. What neurotransmitter is stored in the synaptic vesicles?18. The release of AcH allows what chemical to flow into the cell?19. At rest the muscle cell is (-), what chemical causes an action potential of the cell (cell becomes +)?20. Voltage regulated channels on sarcoplasmic reticulum open when ____________?21. A stimulus causes a wave of ______________ which is going from (-) to (+).22. Put the following events of excitation in chronological order.1. Chemically regulated channels on motor plate open and Na+ goes into cell2. Voltage regulated channels let Ca+2 into nerve cell3. Stimulus causes depolarization4. Voltage regulated channels on terminal cisterna & sarcolemma open, allowing Ca+2 into cell5. Ca+2 ruptures synaptic vesicles and AcH then binds to receptors.23. Where does the majority of the Ca+2 come from during excitation & contraction?24. What are the terminal cisterna made up of?25. What is the main purpose of excitation?26. ________________ is the plasma membrane of a muscle fiber.27. The _________ contains myofilaments.28. ________________ contain thick and thin filaments29. What is the functional unit of skeletal muscle?30. The ________line serves as an anchor for thin filaments31. The ________line serves as an anchor for thick filaments32. Thick filaments = the _____ band.33. The ____ band contains NO thick filaments.34. _____zone is an area of thick filaments where NO thin filaments overlap.ANSWERS 1. Resting potential (-85 mV)2. excitable3. nerve and muscle cells4. Active Channels5. chemically gated6. voltage regulated 7. Action Potential ( - to +)8. Neuromuscular Junction9. motor end plate10. synaptic vesicles11. Excitation Contraction Coupling12. sarcolemma13. T-tubules14. terminal cisterna15. triad16. Ca+217. acetycholine (AcH)18. Na+19. Na+20. have wave of (+) charge = depolarization21. depolarization22. 3-2-5-1-423. terminal cisterna (or inside the cell)24. sarcoplasmic reticulum25. get Ca+2 into cell = increase intracellular Ca+2 levels26. Sarcolemma27. Myofibril28. Myofilaments29. sarcomere30. Z line31. M line32. A band33. I band34. H


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UNCW BIO 240 - Muscle Phys & Muscle Fibers

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