-1-BIOS 100 - Fall 2006 Name:Final Exam, 11 December, 2006Michael Muller, Instructor TA:This exam consists of 52 questions over 5 pages. Please check to see that all the pages are present beforeyou begin. Use a #2 pencil and bubble in all answers. Your score will be posted on the UIC Blackboardsite as soon as they are in. No kidding. Good Luck! 1. Sickle cell anemia is due to a change in amino acid six from Glutamic Acid to Valine in a hemoglobinsubunit. This is an example of a change in protein __________ structure.A. Primary B. Secondary C. Tertiary D. Quaternary2. Which of the following is not a polysaccharide?A. Lactose B. Starch C. Cellulose D. Cholesterol E. Sucrose3. Ions differ in the number of ______ in the atom or molecule.A. Protons B. Neurons C. Electrons D. A & B E. B & C4. Which of the following properties of water is FALSE?A. Water has a high specific heat capacityB. Water has high surface tensionC. Water has strong adhesive but weak cohesive proptertiesD. Liquid water is more dense than solid waterE. Water is a polar molecule (yup, I’ll still fail you if you choose this answer)5. In which bond is carbon the most reduced (D & E are double bonds)?A. C-C B. C-O C. C-N D. C=O E. C=N6. During feedback inhibition:A. The products of the reaction series allosterically regulate an enzyme in the seriesB. The products of the reaction series destroy all of the substratesC. The products of the reaction series act as transcription factors to shut off the reactionD. The products of the reaction series are destroyed by the enzymes in the systemE. The products of the reaction series are not involved in regulation of the reaction series7. Which of the following statements about enzymes is FALSE?A. Most enzymes are proteinsB. The active site is the only site on the enzyme where molecules can bindC. Allosteric regulation of enzymes is commonD. Enzymes function by lowering the activation energy of the reactionE. Enzymes catalyze both the forward and the reverse reaction8. The pH of the blood is 7.4. What do you predict the pH optimum of the enzyme carbonic anhydraseto be?A. 5.0 B. 6.5 C. 7.0 D. 7.4 E. 8.09. Which of the following would you not expect to be associated with a biological membrane?A. Phospholipids B. CholesterolC. Antigens D. Receptor sitesE. DNA binding sites-2-10. Which molecule would you expect to have the most difficulty diffusing across a biologicalmembrane?22 614A. H O B. CO C. Na+ D. C H E. Estrogen11. Which two factors are most responsible in determining the rate of diffusion of a molecule?A. Molecular size and ionic state B. Molecular size and system temperatureC. Ionic state and system temperature D. Molecular size and molecular shapeE. Molecular shape and system temperature12. Which of the following statements about the Na+/K+ pump is FALSE?A. The Na+/K+ pump transports 3 Na+ and 2 K+ across a membraneB. The Na+/K+ pump is an antiportC. The Na+/K+ pump is used to create the resting potential of a neuronD. The Na+/K+ pump is an example of a facilitated diffusion carrier proteinE. The Na+/K+ pump creates a gradient to aid in removal of glucose and vitamins from thefiltrate in a nephron13. From where does PS II (p680) replenish its lost electron during non-cyclic photophosphorylation?222A. H O B. CO C. O D. NADPH E. NADP+14. Which statement about the light-dependent reactions is FALSE?A. Cyclic photophosphorylation produces ATPB. Non-cyclic photophosphorylation produces ATPC. Both cyclic and non-cyclic photophosphorylation utilize PS I (p700)D. Both cyclic and non-cyclic photophosphorylation produce NADPHE. Both cyclic and non-cyclic photophosphorylation occur on the thylakoid membranes15. What are the two substrates utilized by the enzyme Rubisco during the light-independent reactions?22A. NADPH and ATP B. CO and NADPH C. CO and RUBP22D. NADPH and RUBP E. CO and O16. Photorespiration is bad for the plant.A. True B. False 17. Living plant cells contain mitochondriaA. True B. False418. What enzyme fixes carbon in the bundle sheath of a C plant?A. Rubisco B. PEP Carboxylase C. Carbonic AnhydraseD. A & B E. A & C19. When do CAM plants typically open their stomates?A. During the day B. During the night C. When it is rainingD. When it is sunny E. Whenever the hell they want to20. ATP is produced in all of the following EXCEPT:A. Glycolysis B. Conversion of Pyruvate to Acetyl CoAC. Krebs Cycle D. Oxidative Phosphorylation21. What is the final electron acceptor in Oxidative Phosphorylation?222A. NAD+ B. NADH C. O D. CO E. H O-3-22. Which famous scientist or scientific team is incorrectly matched with their contribution to science?A. Hershey & Chase - showed that DNA was the molecule of heredityB. Meselson & Stahl - showed that DNA replication was semi-conservativeC. Avery, McCarthey, & MacLeod - first demonstrated bacterial transformation in StreptococcusbacteriaD. Chargaff - discovered that, in any organism, the number of A=T and the number of C=GE. Freeman - wrote your textbook (and fed me dinner last week - yum!)23. Which enzyme is incorrectly matched with its function?A. Topoisomerase - removes supercoilsB. DNA Polymerase III - uses template to synthesize complementary DNA strand in 5' to 3'directionC. Ligase - seals nicks and gaps in DNAD. Helicase - rewinds unwound DNAE. Primase - creates an RNA primer24. All of the following are necessary for initiation of translation except:A. A large ribosomal subunit B. A small ribosomal subunitC. A mRNA D. A charged tRNA in the P siteE. A charged tRNA in the A site25. During transcription, where does RNA polymerase II bind?A. The promoter B. The operator C. The primase locationD. The TATA box E. None of the above26. When is the rate of transcription of the lac operon the greatest?A. When lactose and glucose are presentB. When lactose is present and glucose is absentC. When lactose is absent and glucose is presentD. When lactose and glucose are absent27. Which form of gene regulation involves TATA binding protein binding to the TATA box?A. Transcription control B. Post-transcription controlC. Translation control D. Post-translation control28. What do restriction endonucleases do?A. Aid in the formation of the 5' Guanine cap in mRNAB. Cut DNA in specific sequences, often leaving sticky endsC. Kill bacteriaD. Join DNA, allowing us to seal DNA in plasmidsE.