-1-BIOS 100 - Summer, 2008 Name:Exam III, 6 Aug, 2008Michael Muller, Instructor TA:This exam consists of 54 questions spread like butter over eight pages. Please check to see that all thepages are present before you begin. Use a #2 pencil and bubble in all answers. The final exam isFriday, 8 August, in Lecture Center F6. Don’t forget that, or you’ll end up wandering around, lonelyand lost! Your score will be posted on the UIC Blackboard site as soon as they are in. Good Luck! 1. Which of the following statements (A-D) about operons is FALSE? If statements A-D aretrue, then choose E.A. Operons are only found in prokaryotes - they are not found in eukaryotesB. Operons may be either inducible or repressibleC. Operons are organizations of genes all under one controlD. Operons typically have a repressor protein which is a DNA-binding proteinE. All of the above statements are TRUE2. What would happen to the lac operon if the repressor protein was mutated so that it couldnever bind to lactose?A. The lac operon would be permanently turned offB. The lac operon would be permanently turned onC. The activity of the lac operon would be under the control of glucose concentrationD. The lac operon could be turned on or off, but it could never be as active as it would bein a cell without the mutationE. None of the above 3. What would happen to the lac operon if the repressor protein was mutated so that it couldnever bind to the operator?A. The lac operon would be permanently turned offB. The lac operon would be permanently turned onC. The activity of the lac operon would be under the control of glucose concentrationD. The lac operon could be turned on or off, but it could never be as active as it would bein a cell without the mutationE. None of the above 4. What would happen to the lac operon if the CAP protein was mutated so that it could neverbind to cAMP?A. The lac operon would be permanently turned offB. The lac operon would be permanently turned onC. The activity of the lac operon would be under the control of glucose concentrationD. The lac operon could be turned on or off, but it could never be as active as it would bein a cell without the mutationE. None of the above 5. In a bacterium, if the concentration of glucose is high, the concentration of cAMP will mostlikely be high.A. True B. False-2-6. Which of the following is NOT and example of post-transcriptional gene regulation ineukaryotes?A. Removal of intronsB. Addition of a 3' poly-A tailC. Transport of the immature mRNA out of the nucleusD. Addtion of a 5' Guanine CapE. All fo the above are post-transcriptional gene regulations found in eukaryotes7. What would you assume about a protein with a leucine zipper?A. It is an enzyme B. It is an integral proteinC. It is a DNA-binding protein D. It is an antigenE. B & D8. What would happen to a cell that was mutated so that its TFIID could never bind to the TATAbox?A. Gene transcription would be unaffectedB. Gene transcription would be more difficult, but genes could still be turned on or offC. Gene transcription of certain regulatory genes would be affected, but the majority ofgene transcription would be unaffectedD. Gene transcription of all genes would be shut down and the cell would soon dieE. None of the above9. The removal of the C-chain in insulin is an example of:A. Chromosome remodeling B. Transcriptional controlC. Post-Transcriptional control D. Translational controlE. Post-Translational control10. What is the function of transcription enhancers?A. They are the binding site of TFIIDB. They help transcription factors bind to DNAC. They help RNA polymerase bind to the promoterD. They help the mRNA bind to the ribosomeE. None of the above11. Which of the following diagrams is of a 2n=8 Cell in Metaphase I of Meiosis?A. B. C. D. E. 12. All normal human somatic cells have 2n=46 chromosomesA. True B. False-3-13. Which of the following statements (A-D) about regulation of the cell cycle are FALSE. Ifstatements A-D are true, then choose EA. There are numerous checkpoints throughout the cell cycle. The cell cycle will stop atthese points until certain conditions are metB. If the cell does not receive the appropriate signals to enter the S-stage of the cell cycle,it will enter the G0 stageC. The G0 stage is a non-dividing stageD. The cell will enter the M stage only when there is a sufficient concentration of MPFE. All of the above statements about regulation of the cell cycle are TRUE14. During which stage of meiosis does crossing over occur?A. Prophase I B. Prophase II C. Metaphase I D. Metaphase IIE. Anaphase I15. During which stage of meiosis do the homologous chromosomes separate?A. Metaphase I B. Metaphase II C. Anaphase I D. Anaphase IIE. Telophase I16. What is the product of meiosisA. Two genetically identical cells B. Two genetically unique cellsC. Four genetically identical cells D. Four genetically unique cellsE. None of the above17. What is a non-disjunction?A. It is what happens when chromosomes fail to cross overB. It is what happens when crossing over switches parts of non- homologouschromosomesC. It is what happens when unequal portions of chromosomes are swapped duringcrossing overD. It is what happens when crossing only occurs between homologous chromosomesE. It is what happens when chromosomes fail to separate properly during meiosis I or II18. Which of the following statements (A-D) about cyclins and associated molecules is FALSE?If statements A-D are true, then choose E.A. Cyclin-dependent kinase (CDK) levels are constant throughout the cell cycleB. Cyclin levels are highest at the end of G2 and beginning of the M stages of the cellcycleC. Cyclins and cylclin-dependent kinases (CDK’s) combine to form maturationpromotion complexes (MPF)D. MPF promotes mitosis and initiates processes to destroy cyclinsE. All of the above statements are TRUE.19. Which of the following cells are produced by a vascular cambium?A. Apical meristem B. Primary xylem C. Secondary xylemD. Root cap E. Pericycle-4-Use the list of cells below to answer questions 20 - 21parenchyma cell sclerenchyma cell collenchyma cellxylem parenchyma tracheid sieve-tube elementpalisade mesophyll companion cell vessel elementvascular cambium cell20. How many of the cells in the above list are dead at functional maturity?A. Two B. Three C. Four D. Five E. Six21. How many of the cells in the