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Penn BIBB 109 - 11-7-12 review

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Slide 1Slide 2Slide 3Slide 4What are some unique features of somatosensory neurons?Slide 6Slide 7Slide 8Slide 9Slide 10Slide 11Slide 12If you ran with scissors and poked your left eye out (you should have listened to your mother!), which of the following would be true?a) There would be no activity in the right visual cortexb) You won’t be able to see anything in the right hemifieldc) Won’t have any activity in every other layer of the lateral geniculate nucleusd) You would get Wallerian degeneration of retinal ganglion cell axons from both eyesIn the visual field below, where would the ON center bipolar cell receptive field have the greatest (most depolarized) response? Least response?What molecular manipulations could you make to block phototransduction?You discover a new neurodegenerative disease in which somatosensory neurons with the smallest axon diameter die off. What sensation would be affected?a) Body senseb) Pain and temperaturec) Normal touchWhat are some unique features of somatosensory neurons?If a patient presents with muscle weakness, what could be the cause?Gamma motor neurons are important for the proper functioning of which reflex(es)?a) Myotaticb) Reverse myotaticc) Flexor-crossed extensord) Both myotatic and reverse myotatice) All of the aboveWhat are some similarities and differences between the basal ganglia and cerebellum?Similarities DifferencesYou stain taste cells with antibodies to the various taste receptors. Based on the level of proteins that you see in each of the 3 cells listed below, draw a graph of the predicted responses these cells would have to various tastants:Taste Cell A- high expression of T2R and low expression of T1R2+T1R3Taste Cell B- high expression of T1R1+T1R3 and amilioride-sensitive ion channel and low expression of T1R2+T1R3Taste Cell C- high expression of a specific sour receptor and medium expression of T2RRate of Action Potential FiringHCl NaCl Quinine Sucrose GlutamateYou think you have discovered a new olfactory receptor. You perform a loss of function experiment to test this by knocking down the receptors in a rat that has been trained to push a button when he smells a new scent. You test over 100 scents, but you don’t notice any that the rat does not respond to by pushing the button. Does this mean that the protein is not an olfactory receptor?1. Yes2. NoIf you express a mutant V-gated Na channel in spiral ganglion cells that take longer to inactivate, the coding of what information would be the most affected?a) Low frequency soundsb) High frequency soundsc) Medium frequency soundsd) Sound intensityWhat are the advantages and disadvantages of using population coding versus labeled line coding?Advantages


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