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Penn BIBB 109 - 10-26-12 Taste

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TasteSlide 2Taste Receptors -saltySlide 4Slide 5Slide 6Temperature receptors also contribute to our taste sensationsTasteTaste is coded in gustatory afferents by:Slide 10Slide 11TasteSlide 13Slide 14SummarySummaryTaste•How do we detect tastants?•How do we code for tastants?•Where does taste information go once we’ve detected it?Tongue and taste cellsTaste Receptors-saltyInside TongueOutside TongueTaste Receptors-sourTaste Receptors-bitter, sweet, and umami•Another salt receptor•Another sour receptor•Fat receptors?Temperature receptors also contribute to our taste sensationsTaste•How do we detect tastes?•How do we code for tastes?•Where does taste information go once we’ve detected it?Taste is coded in gustatory afferents by:a) Population codingb) Labeled line codingTaste CodingA tastant produced the following APs in axons 1-4. What is the identity of the tastant?1234Sucrose NaCl HCl Quinine123412341. Sucrose2. NaCl3. HCl4. QuinineTaste•How do we detect tastes?•How do we code for tastes?•Where does taste information go once we’ve detected it?Taste PathwaysSummarySummary•Taste buds are a cluster of taste cells, which have taste receptors on the apical end and, when stimulated by tastants, release neurotransmitter onto gustatory afferents•Tastants activate taste cells by:–Directly passing through ion channels (salt and sour)–Binding to and blocking ion channels (sour)–Bind to G-protein-coupled receptors (bitter, sweet, umami)•Gustatory afferents use population coding•Gustatory afferents project (as cranial nerves) to the ipsilateral gustatory nucleus in the medulla•Neurons of the gustatory nucleus project to the thalamus, which then project to the primary gustatory cortex located in the insular


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