PHYSIOLOGY4521552 FINAL EXAMINATION Thursday MaY3 2007 INSTRUCTIONS consistsofEQmultiplechoicequestions This examination Pleasep nt your 4 qg and l ig UB p9 9 g C ID 9 clearlv on the 3 ggi 99ll3 llgIg q circleson the aoswersheet in corresponding Fill Pleasemarkyouranswerscarefullyon the answersheetwith a 2 pencil If you erase do so completely Thereis only g4g 9g g45ggg for eachquestion This examconsistsof l pages including this coverpage and Q questions Pleasecheckthatyourcopyhasall pages All questionscarry equal weight readthe questionscarefi rlly Answerswill be postedassoonaspossibleon UBl earns TURN OFF ALL CELL PHONES ANYONE WIIO ANSWERSA CELL PHONE DURING THE EXAM WILL RECEIVE A ZERO O FOR THE EXAM CHEATING ON EXAMS In an effort 10 decreasethe temptationto cheaton houdy and final examswe ask that you follow theprocedweslistedbelow 1 2 3 4 5 Keepyour answersheetglyglg exceptwhen addingan answer When creating your own list of answersto ch ck againstthe key pleasewrite small andbe asdiscreteasPossible Pleaseinform one of the instructorsas soonas possibleifyou suspeclsomeoneis cheating Your commentswill be kept confidential that accordingto Univeisitypolicy a persongivinganswersis equallyas Remember answers guiltyasa personreceiving is dismissalfrom theUniversity penalty for cheating Theultimate The versionofYoUR exarnis VERSION 2 On sidetwo of your answel sheet scanton thereis a Gradeor Education box below the Identification box where you add your studentnumber In tlis Gradeor Education box fill in circle2 Ifyou do not addyour examveNionyouwill receive a zero 0 for this exam Ifyou hll in the WRONGnumber you will be scoredfor thenumberyou fill in ihis is yourresponsibilityonly Ifyou fill in the wrotrg number it cannotbe changed after you turn in Your exam I Which of the following statementsis true Testosterone a b c d e in Sertolicells ofestrogens inhibitssynthesis is not synthesizedin females is a precursorof glucocorticoids is convertedto DHT in targettissues All ofthe above precursor from a cholesterol 2 Whichofthe followinghormonesis synthesized a b c d e l Insulin likeGrowthFactor1 IGFI Epinepbrine 1 25 oH rD Leptin Calcitonin Glycogenis to triglyceridesasglucoseis to a b c d e insulin protein free fatty acids glucagon glycerol 4 Which ofthe following hormonesale secretedfrom the antedorpituitary a Thyroid releasinghormone TRH adrenocorticotropichormone ACTH and groMh hormone GH b Thyroidstimulatinghormone TSH luteinizinghormone LH arldgroMh hormone GH c Insulin likegowth factorI IGFI glucagon andparathltoidhormone PTH CG prolacti andthyroidreleasinghormone TRH d Chorionicgonadotropin e Cofiicotropinreleasinghomone CRH follicle stimulatinghormone FSH and antidiuretichormone ADH 5 Whichofthe followinghormoneshasthe shortesthalflife t in thebloodstream a b c d Parathyroidhomone PTH Epinepfuine Insulin Thyroid hormone Ta Cortisol 6 Which of the following is NqI tue of gonadotropinreleasinghormone GnRH a b c d e It is expressedin both malesandfemales Its releaseis pulsatilein bothmal sandfemales It is absentuntil puberty Thereis a surgein bloodlevelsprior to owlation It is secretedftom neuronsin the hypothalamus a mineralcorticoidbecause is considered 7 Aldosterone a b c d e its primaxytissuetargetis the kidney it is a steroid it is synthesizedin the adrenalgland it Fomotes uptakeof calciumftom the gastrointestinaltract it containsiodine 8 Whathappensto the circulatingconcentrationsof the following hormonesimmediately preceding the recruitmentof a cohortoffollicles a b c d e Both estrogensandprogesteronedecrease andestradiol E2 decreases Inhibinincreases andinhibindecreases FSH follicle stimulatinghormone increases inqease and estogens luteinizing hormone Both LH Noneofthe above calledan anti estrogen sometimes 9 Why is progesterone a In the endom trium it inhibits transcriptionwhile estradiol E2 stimulates transcription arelow andviceversa levelsarehigh estrogens b Becausiwhenbloodprogesterone c It stimulatesthe conversionof estradiol E to the much lesspotentestone El releaseof LH luteinizinghormone andFSH folliclestimulating d It stimulates hormone from the pituitary while estrogensinhibit LH FSH release e All ofthe above 10 Onemonthaffergestation a fetuscouldbe called indifferent because a b c d e it lacksthe SRY gene it hasan XXY genotype it hasno genderPhenoqPe it secretesalrti miilledan hormone sigh itjust doesn tcareanymore 11 Thyroidhormoneandcortisol xelttheirmajoreffectsthroughwhichofthe following a b c d e Transcription Tyosine kinase DNA replication Translation Noneofthe above cells 12 Whatpropertyis sharedby Sertolicells folliculargranulosa a b c d e The presenceof aromatas of FSHreceptors Thepresence They secreteinhibin A B o ttl y All ofthe above factor mD by the 96 weekofgestation testesdetermining 13 lf a fetushasnot expressed a b c d e it will developasa female the Wolffian duct will developinto ovariesand otherfemale specificorgans it will not expressandrogens it will developgonadaldysgenesis All ofthe above in the adrenalgland 14 Whichofthe followingis Q synthesized a b c d e Aldosterone Androgens Cortisol Estrogens Noneofthe above I 5 Which of the following is NQI true of ca lcium a b c d e It inhibits protein kinaseC It is storedprimarilyin bone synthesis 24 25 OH D3 in the bloodresultin increased High concentralions receptors ftom intercellularstorcsby the actionsofGo coupled It is released peptide hormone secretion stimulates stores usually ofintercellular Release 16 Turbulencein blood flow can genelatea heartmumur whenarterialblood passesthrougha narrowheartvalve openingor whenblood leaksbackwardthrougha leaky valve ln the following statem ntswhich is NQI true a A murmurthat occus du ng ventdcularsystolecould representblood flow through a narrowaortic valve opening b A mulmur that occursduring ventricularsystolecould representblood flow thougha leakymitral valve A mulmw that occursduring diastolecould representbackwardblood flow through c a leakymital valve d A murmur that occus during systolecould representblood flow through a nanow pulmonaryvalve opening e A murmurthatoccursduringdiastolecould representbackwardblood flow though a leaky aortic valve 17 Sinusrateis regulatedby autonomicnervoussystemtone ln the followingstatements which is NQf true morc in heartratechanges nervestimulationthe increase a Followingsympathetic slowly than doesthe decreasein heartrate following parasympatheticnerve stimulation b In the presenceof a